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Virus Discovery by Metagenomics: The (Im)possibilities
Since the late 1800s, the discovery of new viruses was a gradual process. Viruses were described one by one using a suite of techniques such as (electron) microscopy and viral culture. Investigators were usually interested in a disease state within an organism, and expeditions in viral ecology were rare. The advent of metagenomics using high-throughput sequencing has revolutionized not only the rate of virus discovery, but also the nature of the discoveries. For example, the viral ecology and etiology of many human diseases are being characterized, non-pathogenic viral commensals are ubiquitous, and the description of environmental viromes is making progress. This Frontiers in Virology Research Topic showcases how metagenomic and bioinformatic approaches have been combined to discover, classify and characterize novel viruses.
Handbook of Molecular Microbial Ecology I
The premiere two-volume reference on revelations from studying complex microbial communities in many distinct habitats Metagenomics is an emerging field that has changed the way microbiologists study microorganisms. It involves the genomic analysis of microorganisms by extraction and cloning of DNA from a group of microorganisms, or the direct use of the purified DNA or RNA for sequencing, which allows scientists to bypass the usual protocol of isolating and culturing individual microbial species. This method is now used in laboratories across the globe to study microorganism diversity and for isolating novel medical and industrial compounds. Handbook of Molecular Microbial Ecology is the fi...
Introduction to Molecular Genomics
Introduction to Molecular Genomics introduces the college student to the fundamental concepts of molecular biology and genomics. The text puts an emphasis on important topics in the subject that contribute to the learner’s understanding. These topics include molecular genomics, biodiversity and molecular phenomenon behind evolution of species, modern molecular methods for enhanced genomics research, DNA modifications at the molecular level for transgenic animal species, the role of cell environment on the gene expression, to name a few. The book has been designed to suit the requirements of educational courses in molecular biology, genomics and biochemistry. Key features - Covers basic concepts on key topics in molecular biology and genomics - Simple easy-to-read layout - Includes references for further reading - Includes a section on ethical aspects of scientific research Introduction to Molecular Genomics is a simple primer for students in applied or advanced life science courses at undergraduate levels
Virus Bioinformatics
Virus bioinformatics is evolving and succeeding as an area of research in its own right, representing the interface of virology and computer science. Bioinformatic approaches to investigate viral infections and outbreaks have become central to virology research, and have been successfully used to detect, control, and treat infections of humans and animals. As part of the Third Annual Meeting of the European Virus Bioinformatics Center (EVBC), we have published this Special Issue on Virus Bioinformatics.
The New Foundations of Evolution
This is the story of a profound revolution in the way biologists explore life's history, understand its evolutionary processes, and reveal its diversity. It is about life's smallest entities, deepest diversity, and greatest cellular biomass: the microbiosphere. Jan Sapp introduces us to a new field of evolutionary biology and a new brand of molecular evolutionists who descend to the foundations of evolution on Earth to explore the origins of the genetic system and the primary life forms from which all others have emerged. In so doing, he examines-from Lamarck to the present-the means of pursuing the evolution of complexity, and of depicting the greatest differences among organisms. The New F...
Microbial Nexus for Sustainable Wastewater Treatment
Microbial ecology is pivotal in wastewater treatment, where microorganisms play a vital role in breaking down organic matter and ultimately reduce the levels of contaminants in treated water, making it safe for reuse in agriculture, industry, and other applications. The book, Microbial Nexus for Sustainable Wastewater Treatment: Resources, Efficiency, and Reuse, ventures into the dynamic world of microbial ecosystems, unveiling their pivotal role in reshaping wastewater treatment technologies. This book addresses novel microbial techniques related to sustainable, efficient technologies of wastewater treatment and wastewater reuse as well as obtaining high-quality effluents from treatment pla...
The Origin and Nature of Life on Earth
Uniting the foundations of physics and biology, this groundbreaking multidisciplinary and integrative book explores life as a planetary process.
The Gut Microbiome
The influence of the gut microbiome on human health and disease has been established in recent years through advances in high-throughput DNA sequencing. The Gut Microbiome: Bench to Table presents a scientific introduction to this topic, analyzes research on how the microbiome is affected by nutrients, and how dietary modifications can alter the microbiome. The Gut Microbiome: Bench to Table is divided into three sections. The first section details the current state of laboratory-scale analysis of gut microbiome samples and how we can identify the communities and their functional repertoire. Section II explains the next phase of translational research models such as preclinical, animal studi...
Pattern Recognition in Bioinformatics
This book constitutes the refereed proceedings of the 6th International Conference on Pattern Recognition in Bioinformatics, PRIB 2011, held in Delft, The Netherlands, in November 2011. The 29 revised full papers presented were carefully reviewed and selected from 35 submissions. The papers cover the wide range of possible applications of bioinformatics in pattern recognition: novel algorithms to handle traditional pattern recognition problems such as (bi)clustering, classification and feature selection; applications of (novel) pattern recognition techniques to infer and analyze biological networks and studies on specific problems such as biological image analysis and the relation between sequence and structure. They are organized in the following topical sections: clustering, biomarker selection and classification, network inference and analysis, image analysis, and sequence, structure, and interactions.
Eco-Restoration of Polluted Environment
The book Eco-Restoration of the Polluted Environment: A Biological Perspective explores recent advances in biological strategies for the remediation of polluted environments, including soil, water, and air. It covers bioremediation of heavy metals, radioactive waste, and waste gases, which are believed to be bottleneck problems for researchers working in this field. The book contains separate chapters on genetic engineering technology for enhancement of the bioremediation potential of bioresources and the role of biosurfactants, enzymes, and exo-polysaccharides for bioremediation of polluted environments, along with basic aspects of eco-restoration by microorganisms. It summarizes the signif...
