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Cellular Nanomachines
In this book, the major paradigm-shifting discoveries made in the past century on key cellular nanomachines are described in great detail: their complex yet precise and elegant design and function, as well as the diseases linked to their dysfunction and the therapeutic approaches to overcome them. The major focus of this book is the “porosome” nanomachine, the universal secretory portal in cells. This is an ideal book for students, researchers, and professionals in the fields of nanoscience and nanotechnology.
NanoCellBiology of Secretion
Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Over the past 15 years, there has been a renewed understanding of living cells at the molecular level. Atomic Force Microscopy, Laser Force Microscopy, single secretory vesicle patch clamp studies, highresolution electron microscopy, and x-ray diffraction, are some of the tools now being used to unravel the intricacies of a living cell at the molecular level. Opening with an explanation of Materials and Methods, NanoCellBiology then moves through discussions of porosome discovery, calcium and SNARE-induced fusion, and vesicle swelling before winding up in a final chapter of conclusions and future studies. Succinctly packaged as SpringerBrief, this book is a must for those studying or conducting research in cell biology, biochemistry or nanobiology/nanotechnology. This book will be invaluable to faculty & graduate students involved in Nano Courses; Cell Biology Courses; Biophysics Courses; and Biochemistry Courses as well as practicing Cell Biologists, Biochemists and BioPhysicists.
NanoCellBiology
This book provides a comprehensive understanding of the discovery of a new cellular structure the "porosome," which is the universal secretory machinery in cells; the protein assembly, biomineralization, and biomolecular interactions; the molecular evolution of protein structure; the use of magnetic nanoparticles for transformative application in medicine and therapy, and the new and novel imaging approach of electrical impedance spectroscopy in biology. It be used for college courses in nanomedicine, nano cell biology, advanced nanotechnology, and biotechnology at the undergraduate and graduate level.
Methods in Nano Cell Biology
Understanding live cells at the single molecule level is the most important and single major challenge facing biology and medicine today. Nanobiology focuses on the properties and structure of complex assemblies of biomolecules—biochips and molecular motors, for example—in conjunction with distinctive surfaces, rods, dots, and materials of nanoscience. Nano Cell Biology will describe the current applications of nanobiology to the study of the structure, function, and metabolic processes of cells. Provides historical background on this newly emerging field Covers the latest application of new instrumentation in the field Detailed protocols in the study of live cells at the nanometer level Discusses future technologies and their applications in the study of living cells
Atomic Force Microscopy in Cell Biology
This is the first book to cover the history, structure, and application of atomic force microscopy in cell biology. Presented in the clear, well-illustrated style of the Methods in Cell Biology series, it introduces the AFM to its readers and enables them to tap the power and scope of this technology to further their own research. A practical laboratory guide for use of the atomic force and photonic force microscopes, it provides updated technology and methods in force spectroscopy. It is also a comprehensive and easy-to-follow practical laboratory guide for the use of the AFM and PFM in biological research.
Force Microscopy
A complete examination of the uses of the atomic force microscope in biology and medicine This cutting-edge text, written by a team of leading experts, is the first detailed examination of the latest, most powerful scanning probe microscope, the atomic force microscope (AFM). Using the AFM, in combination with conventional tools and techniques, readers gain a profound understanding of the cell, subcellular organelles, and biomolecular structure and function. The text begins with three chapters describing the molecular machinery and mechanism of cell secretion and membrane fusion in cells, using approaches that combine AFM, electron microscopy, X-ray diffraction, photon correlation spectrosco...
Aquaporin Regulation
Aquaporin Regulation, Volume 112, the latest release in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters highlighting Perspectives on the evolution of aquaporin superfamily, Structure and dynamics of aquaporin-1, Selectivity and Transport in Aquaporins from Molecular Simulation Studies, Aquaporin regulation in metabolic organs, Phosphorylation of human AQP2 and its role in trafficking, Regulation of Aquaporin-2 by RNA Interference, Aquaporin Regulation: Lessons from Secretory Vesicles, CFTR Regulation of Aquaporin-mediated Water Transport, Glucocorticoid Gene Regulation of Aquaporin-7, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Vitamins and Hormones series Updated release includes the latest information on aquaporin regulation
Cell Imaging Techniques
A diverse collection of state-of-the-art methods for the microscopic imaging of cells and molecules. The authors cover a wide spectrum of complimentary techniques, including such methods as fluorescence microscopy, electron microscopy, atomic force microscopy, and laser scanning cytometry. Additional readily reproducible protocols on confocal scanning laser microscopy, quantitative computer-assisted image analysis, laser-capture microdissection, microarray image scanning, near-field scanning optical microscopy, and reflection contrast microscopy round out this eclectic collection of cutting-edge imaging techniques now available. The authors also discuss preparative methods for particles and cells by transmission electron microscopy.
Growth Factors and the Ovary
The First Ovarian Workshop was held in June 1976; its goal was to achieve a collective understanding of current thought on ovarian follicular development and function, and to generate clear definitions of the most important areas to be explored in the future. The Ovarian Workshops quickly became a major biennial event for the community of reproduc tive biologists and their students studying ovarian function. As a young graduate student, I gave my first scientific presentation at the First Ovarian Workshop and I have attended all but one of the subsequent meetings. The Workshops provided a unique forum for the sharing ofideas with colleagues studying closely related problems. I was therefore ...
