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Computational Methods in Systems Biology
This book constitutes the refereed proceedings of the 16th International Conference on Computational Methods in Systems Biology, CMSB 2018, held in BRNO, Czech Republic, in September 2018. The 15 full and 7 short papers presented together with 5 invited talks were carefully reviewed and selected from 46 submissions. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology; parameter and model inference from experimental data; automated parameter and model synthesis; model integration and biological databases; multi-scale modeling and analysis methods; design, analysis, and verification methods for synthetic biology; methods for biomolecular computing and engineered molecular devices. Chapters 3, 9 and 10 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Automated Reasoning for Systems Biology and Medicine
This book presents outstanding contributions in an exciting, new and multidisciplinary research area: the application of formal, automated reasoning techniques to analyse complex models in systems biology and systems medicine. Automated reasoning is a field of computer science devoted to the development of algorithms that yield trustworthy answers, providing a basis of sound logical reasoning. For example, in the semiconductor industry formal verification is instrumental to ensuring that chip designs are free of defects (or “bugs”). Over the past 15 years, systems biology and systems medicine have been introduced in an attempt to understand the enormous complexity of life from a computat...
Hybrid Systems: Computation and Control
This volume contains the proceedings ofthe 11th Workshop on Hybrid Systems: Computation and Control (HSCC 2008) held in St. Louis, Missouriduring April 22–24,2008.The annual workshop on hybrid systems focuses on researchin - bedded,reactivesystemsinvolvingtheinterplaybetweensymbolic/switchingand continuous dynamical behaviors. HSCC attracts academic as well as industrial researchers to exchange information on the latest developments of applications and theoretical advancements in the design, analysis, control, optimization, and implementation of hybrid systems, with particular attention to embedded and networked control systems. New for this year was that HSCC was part of the inaugural CPS...
DNA Computing and Molecular Programming
This book constitutes the refereed proceedings of the 19th International Conference on DNA Computing and Molecular Programming, DNA 19, held in Tempe, AZ, USA, in September 2013. The 14 full papers presented were carefully selected from 29 submissions. The papers are organized in many disciplines (including mathematics, computer science, physics, chemistry, material science and biology) to address the analysis, design, and synthesis of information-based molecular systems.
Hybrid Systems Biology
This book constitutes the thoroughly refereed proceedings of the 6th International Workshop on Hybrid Systems Biology, HSB 2019, held in Prague, Czech Republic, in April 2019. The 8 full papers presented in this book together with 1 short paper and 3 invited papers were carefully reviewed and selected from 13 submissions. They cover topics such as: modeling and analysis of metabolic, signaling, and genetic regulatory networks in living cells; models of tissues, organs, physiological models; models and methods coping with incomplete, uncertain and heterogeneous information including learning for biological systems, parametric synthesis and inference; stochastic and hybrid models in biology; h...
Formal Methods for Control of Nonlinear Systems
Formal methods is a field of computer science that emphasizes the use of rigorous mathematical techniques for verification and design of hardware and software systems. Analysis and design of nonlinear control design plays an important role across many disciplines of engineering and applied sciences, ranging from the control of an aircraft engine to the design of genetic circuits in synthetic biology. While linear control is a well-established subject, analysis and design of nonlinear control systems remains a challenging topic due to some of the fundamental difficulties caused by nonlinearity. Formal Methods for Control of Nonlinear Systems provides a unified computational approach to analysis and design of nonlinear systems. Features Constructive approach to nonlinear control. Rigorous specifications and validated computation. Suitable for graduate students and researchers who are interested in learning how formal methods and validated computation can be combined together to tackle nonlinear control problems with complex specifications from an algorithmic perspective. Combines mathematical rigor with practical applications.
DNA Computing and Molecular Programming
This book constitutes the refereed proceedings of the 20th International Conference on DNA Computing and Molecular Programming, DNA 20, held in Kyoto, Japan, in September 2014. The 10 full papers presented were carefully selected from 55 submissions. The papers are organized in many disciplines (including mathematics, computer science, physics, chemistry, material science and biology) to address the analysis, design, and synthesis of information-based molecular systems.
Tools and Algorithms for the Construction and Analysis of Systems
This book constitutes the refereed proceedings of the 13th International Conference on Tools and Algorithms for the Construction and Analysis of Systems, TACAS 2007, held in Braga, Portugal. Coverage includes software verification, probabilistic model checking and markov chains, automata-based model checking, security, software and hardware verification, decision procedures and theorem provers, as well as infinite-state systems.
Molecular Logic and Computational Synthetic Biology
This book collects the revised selected proceedings of the First International Symposium in Molecular Logic and Computational Synthetic Biology ( MLCSB), held in Chile, Santiago, in December 2018. The volume contains 7 full revised papers along with 2 surveys from 19 submissions presented at the symposium. One of the goals of the MLCSB 2018 was to explore the potential of molecular logic frameworks to study the emerging behavioural patterns in biological networks, combining discrete, continuous and stochastic features, and resorting both to specific or general-purpose analysis and verification techniques.
