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Drug Discovery Toxicology
As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug safety experiments are both practical and useful • Covers a variety of key topics – safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and –omics tools • Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods • Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices
Gesundheitswissen aus Behördenhand
Zahlreiche Bundeseinrichtungen erfullen historisch traditionsreiche Aufgaben der Ressortforschung im Gesundheitsbereich. Sie nehmen als Teile der Bundesverwaltung komplexe Relaisfunktionen zwischen Wissenschaft, Politik sowie administrativer Rechtsanwendung wahr. Manche Einrichtungen wie das Robert Koch- oder das Paul-Ehrlich-Institut haben in der Corona-Pandemie als Akteure staatlicher Wissensgenerierung breite Bekanntheit erlangt. Aber auch andere - wie das Friedrich-Loeffler-Institut oder die Bundesinstitute fur Arzneimittel und Medizinprodukte und fur Risikobewertung - verfugen uber leistungsstarke Forschungsabteilungen und agieren durch Forschung und Publikation als aktive Teilnehmer im Wissenschaftsprozess. Die Untersuchung spurt der Geschichte der Einrichtungen, ihrer Funktion im demokratischen Rechtsstaat, ihrer Unabhangigkeit und ihrer Bedeutung fur rechtliche Entscheidungsverfahren nach.
Cancer Research
None
Directory of Graduate Research
Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada.
The Quantum Magician
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Hearts Under Siege
North and South. Enemies and Lovers. War lands on the south's doorstep. Leaving no one unscathed. Brittany Couvion must do her part to save the Confederacy. Brandon McIntyre fights battles of his own. A standalone story that introduces new characters into best-selling author Kathryn Kaleigh's American historical romance series. Skye Travels. Just the beginning... Begin Again is the first of the series, but the books can be read in any order. Savannah Richards did not believe in chance. But there he stood, head bent, focused on his iPad. His hair graying a bit around the edges. Noah would not recognize her, even if he remembered her. Putting the past behind them, they strive to forge somethin...
Southern Belle Civil War - The Couvians
North and South. Enemies and Lovers. Two standalone American historical romance novels. Twins. One sister. One brother. One country turned against itself. HEARTS UNDER SIEGE War lands on the south's doorstep. Leaving no one unscathed. Brittany Couvion must do her part to save the Confederacy, even putting her own life in danger. Brandon McIntyre fights battles of his own and will do whatever it takes to protect Brittany. With danger at every corner, will either of them survive? An enchanting and spellbinding historical romance set against the backdrop of the American Civil War. HEARTS UNDER FIRE Following a steamboat explosion, Southerner Jeffrey Couvion must make a choice no man should have...
Handbook of Radiopharmaceuticals
Sorgfältig aktualisierte Neuauflage dieses wegweisenden Referenzwerk der radiopharmazeutischen Wissenschaften Die 2. Auflage des Handbook of Radiopharmaceuticals wirft einen umfassenden analytischen Blick auf das Fachgebiet und bietet aktuelle Informationen zu zentralen Themen, u. a. die Herstellung von Radionukliden, synthetische Methoden, Entwicklungen in der Radiopharmazie, Regelwerke, und zu einer Fülle praktischer Anwendungen. Als wertvolles Nachschlagewerk für Einsteiger und erfahrene Praktiker untersucht diese Publikation die neuesten Konzepte und Fragestellungen unter Berücksichtigung des gezielten Einsatzes diagnostischer und therapeutischer Radiopharmazeutika. Die Beiträge sta...
Biomarkers in Drug Development
Discover how biomarkers can boost the success rate of drug development efforts As pharmaceutical companies struggle to improve the success rate and cost-effectiveness of the drug development process, biomarkers have emerged as a valuable tool. This book synthesizes and reviews the latest efforts to identify, develop, and integrate biomarkers as a key strategy in translational medicine and the drug development process. Filled with case studies, the book demonstrates how biomarkers can improve drug development timelines, lower costs, facilitate better compound selection, reduce late-stage attrition, and open the door to personalized medicine. Biomarkers in Drug Development is divided into eigh...
