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Textbook of Surgery is a core book for medical and surgicalstudents providing a comprehensive overview of general andspeciality surgery. Each topic is written by an expert in thefield. The book focuses on the principles and techniques of surgicalmanagement of common diseases. Great emphasis is placed onproblem-solving to guide students and junior doctors through theirsurgical training. Throughout the book are numerous reproducible line drawings,tables and boxes that will prove invaluable for learning andrevision. In addition there are detailed guidelines provided forsurgical management. Up-to-date and ideal for medical students and junior doctors onsurgical attachments and a perfect refresher for RACS and MRCScandidates. Reviews of the last edition “The textbook presents a compact and contemporary overviewand is not so much a reference book as a working tome suitable forfamiliarization with current trends in treatment and diagnosis inthese various areas. …found this textbook very informative and a pleasure toread.” ANZ Journal of Surgery Vol. 72, No. 12.
In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleot...
2011 Updated Reprint. Updated Annually. Cyprus Customs, Trade Regulations and Procedures Handbook
This book presents a collection of recent articles published in peer reviewed journals. The articles provide clinicians and trainees with the latest information in the field of diabetology. Divided into twelve sections the yearbook begins with an overview of basic science and epidemiology, followed by discussion on Type 1 diabetes and gestational diabetes. The next sections cover comorbidities, complications, therapeutics, paramedical care, research, and new technologies and guidelines. For each article, the authors provide background information, key learning points, strengths and limitations of the study, and a ‘take home’ message. Each article is accompanied by detailed references for further reading. Key points Collection of recent articles on diabetes published in peer reviewed journals In depth discussion on Type 1 diabetes and gestational diabetes Authors provide background information and summaries for each article Detailed references for further reading
Exploring the contractile activity of smooth muscle segments isolated from various organs of healthy animals and animals with experimentally induced diabetes, she obtained original data about angiotensin II-induced force and time parameters. For the first time, she established the effect of ghrelin on angiotensin II-provoked contraction of the urinary bladder. Original data on the role of both types of angiotensin receptors for the contractile activity of the various segments of the gastrointestinal tract and bladder were obtained. By applying specific software for force and time parameter analysis, the contribution of different types of angiotensin receptors on muscle contractility has been shown. The new methodology was used to analyze the data obtained during the registration of smooth muscle relaxation activity, which allows the determination of not only the magnitude of the mechanical response but also the parameters related to the time and speed of the contractions. Plasma renin activity models have been developed using mathematical approaches to predict the effect of different drug doses on the behavior of the system.
The assassination of President Kennedy in 1963 continues to be shrouded in mystery and controversy. In Plausible Denial, Mark Lane, the author of Rush to Judgment, the provocative and bestselling critique of the Warren Commission, reveals startling evidence about the CIA’s involvement in a plot to murder the president. In 1978, when a small magazine ran a story by CIA renegade Victor Marchetti linking ex-CIA operative and convicted Watergate burglar E. Howard Hunt to the assassination, Hunt sued for defamation. Lane signed on as defense counsel for the publication, and set out to prove the truth of the allegations against Hunt and the CIA. Lane’s investigation uncovered a web of conspira...
The growing knowledge on tumor-immune response interactions and on the tumor microenvironment did not translate so far into better control of cancer by anti-tumor vaccination. The percentage of patients who benefited from vaccination strategies is still too small to justify their general use. It is the aim of this book to present an alternative to the conventional approach of developing injected tumor vaccines to activate anti-tumor immunity, which will fight cancer. It is argued that in situ tumor ablation (destruction) that involves tumor antigen release; cross presentation and the release of danger associated molecular patterns (DAMPs) can make the tumor its own cellular vaccine. Tumor ab...