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The eye is the most easily accessible site for topical administration of a medication. Drugs are commonly applied to the eye for localised action on the surface or in the interior of the eye. A major problem in ocular therapeutics is the attainment of an optimal drug concentration at the site of action. Poor bioavailability of drugs from ocular dosage forms is mainly due to the precorneal loss factors which include tear dynamics, non-productive absorption, transient residence time in the cul-de-sac, and the relative impermeability of the corneal epithelial membrane. Due to these physiological and anatomical constraints only a small fraction of the drug, effectively 1% or even less of the ins...
Translated from 《大眼鸡 越洋人》, a book shortlisted for 2018 Singapore Literature Prize (creative non-fiction, Chinese) by the Singapore Book Council. This book is dedicated to the Cantonese pioneers who voyaged to Nanyang and contributed to the contemporary Singapore. The term guanghuizhao (å¹¿æƒ è‚‡, referring to Guangzhou 广州, Huizhou æƒ å·ž and Zhaoqing 肇庆) for Cantonese is not only a geographical concept, but also a century-old brand in Singapore. Over generations, Kwong Wai Siew Peck San Theng and Kwong Wai Shiu Hospital remain immovable in Singapore, and the Yangzheng Foundation continues to serve the people, breaking a stereotypical view of the community, in which â€...
Laser has been used in dermatology for over four decades. The concept of selective photothermolysis has transformed our understanding of laser tissue interactions, and there has been an explosive interest in laser treatment for both skin diseases and aest
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.