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Brain Networks for Studying Healthy and Pathological Aging Mechanisms and Intervention Efficacy
Previous studies showed that both healthy and pathological aging are associated with changes in brain structure and function of the mature human brain. The most prominent anatomical alteration are changes in prefrontal cortex morphology, volume loss and reduced white-matter integrity and hippocampal atrophy. Cognitive decline affects mainly the performance of episodic memory, speed of sensory information processing, working memory, inhibitory function and long-term memory. It has been also proposed that due to the aforementioned changes the aging brain engages in compensatory brain mechanism such as a broader activation of cortical regions (mainly frontal) rather than specialized activation....
Handbook of Research on Innovations in the Diagnosis and Treatment of Dementia
Technology is playing an increasing role in the lives of the elderly. One of the most prevalent developments for the aging population is the use of technological innovations for intervention and treatment of individuals with mental impairments. The Handbook of Research on Innovations in the Diagnosis and Treatment of Dementia offers empirical research and theoretical analyses on the cognitive impairment of the aging. Featuring studies in gerotechnology, this book is an essential resource for researchers, students, and practitioners in the field of geriatrics who are interested in the emerging research, clinical practices, therapy, and technological innovations concerning the development and treatment of dementia.
The Alzheimer's Disease Challenge
Alzheimer’s disease is undoubtedly the major health challenge of our Century with significant social and economic consequences. This Frontiers eBook offers a contribution of 39 innovative papers on the multidimensional and crucial problem of Alzheimer’s disease management and treatment. Several perspectives, research updates, and trials describing methods on potential diagnosis and treatment are presented including biological mechanisms, biomarkers and risk factors for an early and efficient prognosis, diagnosis and prevention. Additionally, while the rapidly increasing Alzheimer’s disease population demands holistic solutions and clinical studies with new therapeutic target approaches, several of the contributive papers present promising drugs targeting Alzheimer’s disease treatment. We give our deepest acknowledgment to all the authors for their important and innovative contributions, to the reviewers for their valuable recommendations on improving the submitting studies and all the Frontiers Editorial team for continuous support.
Improving the Quality of Life for Dementia Patients through Progressive Detection, Treatment, and Care
The prominence of dementia within the global aging population has undergone an increase in recent years. To improve the living conditions of patients, researchers must place more emphasis on early detection methods. Improving the Quality of Life for Dementia Patients through Progressive Detection, Treatment, and Care provides a thorough overview of emerging research on various neuroscience methods for the early diagnosis of dementia and focuses on the improvement of healthcare delivery to patients. Highlighting relevant issues on health information systems, behavioral indicators, and treatment methods, this book is a pivotal reference source for health professionals, neuroscientists, upper-level students, practitioners, and researchers interested in the latest developments within the field of dementia treatment.
Medical Informatics in a United and Healthy Europe
This volume contains the proceedings of the twenty-second International Conference on Medical Informatics Europe MIE 2009, that was held in Sarajevo, Bosnia and Herzegovina, from 30 August to 2 September 2009. The scientific topics present in this proceedings range from national and trans-national eHealth roadmaps, health information and electronic health record systems, systems interoperability and communication standards, medical terminology and ontology approaches, and social networks to Web, Web 2.0, nd Semantic Web solutions for patients, health personnel, and researchers. Furthermore, they include quality assurance and usability of medical informatics systems, specific disease management and telemedicine systems, including a section on devices and snsors, drug safety, clinical decision support and medical expert systems, clinical practice guidelines and protocols, as well as issues on privacy and security. Moreover, bioinformatics, biomedical modeling and simulation, medical imaging and visualizatio and, last but not least, learning and education through medical informatics systems are parts of the included topics.
Neurophysiology in Alzheimer's Disease and Dementia
Alzheimer's disease (AD) and dementia are the most common neurodegenerative disorder. Since the number of individuals with AD and dementia is expected to increase considerably in the near future, reliable treatment and diagnosis are critical. EEG and neurophysiological technique could be used as a cost-effective screening tool for early detection and diagnosis in the Mild Cognitive Impairment (MCI) stage. The aim in neurophysiology research is to develop signal processing methods that improve the specificity for diagnosing dementia; we wish to discover signal features that not only significantly differ in AD patients, but also allow us to reliably separate AD patients and control subjects. T...
Long-Term Consequences of Adolescent Drug Use: Evidence from Pre-Clinical and Clinical Models
The purpose of this collection is to provide a forum to integrate pre-clinical and clinical investigations regarding the long-term consequences of adolescent exposure to drugs of abuse. Adolescence is characterized by numerous behavioral and biological changes, including substantial neurodevelopment. Behaviorally, adolescents are more likely to engage in risky activities and make impulsive decisions. As such, the majority of substance use begins in adolescence, and an earlier age of onset of use (<15 yr) is strongly associated with the risk for developing a substance use disorder later in life. Furthermore, adolescent drug use may negatively impact ongoing neurological development, which cou...
Speech Enhancement, Modeling and Recognition- Algorithms and Applications
This book on Speech Processing consists of seven chapters written by eminent researchers from Italy, Canada, India, Tunisia, Finland and The Netherlands. The chapters covers important fields in speech processing such as speech enhancement, noise cancellation, multi resolution spectral analysis, voice conversion, speech recognition and emotion recognition from speech. The chapters contain both survey and original research materials in addition to applications. This book will be useful to graduate students, researchers and practicing engineers working in speech processing.
