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BACE
BACE inhibitors and their use in the treatment of Alzheimer's Disease BACE (β-site of APP cleaving enzyme) is a critical component in Alzheimer's Disease (AD), and the development of BACE inhibitors shows great potential as a therapy for the disease. BACE: Lead Target for Orchestrated Therapy of Alzheimer's Disease covers virtually all aspects of BACE from initial identification, discovery of inhibitors, and challenges in clinical development, while providing a global understanding essential for productive and successful drug discovery. This book details the story of the discovery of BACE and its role in AD and comprehensively discusses: The development of BACE inhibitors as therapeutics fo...
The Cambridge Review
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Legal English
First Published in 2012. Routledge is an imprint of Taylor & Francis, an informa company.
The Cambridge Review
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Environmental Magnetism
Magnetism is important in environmental studies for several reasons, the two most fundamental being that most substances exhibit some form of magnetic behavior, and that iron is one of the most common elements in the Earth's crust. Once sequestered in a suitable material, magnetic particles constitute a natural archive of conditions existing in former times. Magnetism provides a tracer of paleo-climatic and paleo-environmental conditions and processes.Environmental Magnetism details the occurrence and uses of magnetic materials in the natural environment. The first half of the volume describes the basic principles. The second half discusses the applications of magnetic measurements in various environmental settings on land, in lakes, in the ocean, and even various biological organisms.* Material is broadly applicable to environmental studies* Case histories illustrate key points* Extensive bibliography makes further research quick and easy
Managing Institutional Recordings
Institutional recordings represent a significant portion of the scholarly output of academic music schools and departments. Audio and video recordings of faculty recitals, student recitals, ensembles, and guest artists provide a unique record of musical life in an academic environment. Libraries have often been responsible for describing, preserving, and providing access to these valuable collections. Managing Institutional Recordings brings together a variety of articles on different aspects of collecting and managing institutional recording collections. This compilation of essays and case studies, written by known experts in the field, explores solutions to managing collections in a variety of institutions across North America. Topics include planning, managing, cataloging, preservation, and legal aspects of collections. As a unique exploration of the topic, Managing Institutional Recordings will provide readers with resources and guidance on their own institutional recording collections.
Letters on the Go
Suzanne Aubert's life was a very full one, ninety-one years packed with eventfulness. It was nonetheless a thoughtful life, in a partnership of reflection and action lived out and communicated to others. The small French nun who strode the streets and roads of New Zealand on behalf of the poor and neglected was in her lifetime a legend - and she has remained so ever since. Highly articulate in both French and English, she wrote copious letters throughout her long life. The correspondence selected here reflects every aspect of her interest - her rich friendships, her challenges to the church hierarchy, her engagement with politicians on behalf of the poor, her relationships with the Sisters of the religious congregation that she founded (the Daughters of the Compassion). This book of letters is a superb presentation of a key figure in New Zealand history.
