Welcome to our book review site go-pdf.online!
You may have to Search all our reviewed books and magazines, click the sign up button below to create a free account.
The Oxford Magazine
None
The Epothilones: An Outstanding Family of Anti-Tumor Agents
Epothilones have received unusual attention over the past ten years. They are novel antitumor drugs which very much like their predecessor paclitaxel (Taxol) act via microtubule stabilization. In comparison to paclitaxel and a number of alternative drugs with a similar mode of bioaction (e.g. laulimalide, eleutherobin, peluroside, discodermolide) the epothilones have significant advantages, above all very high activity in the nanomolar range and low susceptibility towards multidrug resistance. Epothilone B and several derivatives thereof are in phase I-III clinical trials; one of them (ixabepilone, BMS) is already on the market, others are supposed to appear on the market in the near future. All naturally occurring epothilones have been isolated from Sorangium cellulosum; their antitumor action is traced back to the stabilization of microtubules. In consequence, the formation of the mitototic spindle is prohibited and the cell undergoes apoptosis.
Nineteenth-Century Emigration of "Old Lutherans" from Eastern Germany (Mainly Pomerania and Lower Silesia) to Australia, Canada, and the United States
As Mr. Smith has noted in the Introduction to this work, "There is little so rare in German-American genealogy as a complete emigrant passenger list from Bremen." As most researchers know, the Bremen lists were destroyed during the fire storm of that city during World War II. In the case of this work, however, Mr. Smith was able to recover fourteen Bremen lists because they had been reprinted in the obscure weekly newspaper from Rudolstadt, Thuringia, entitled the "Allgemeine Auswanderungs-Zeitung" (which can be found in the rare-book collection at Yale University). The compiler has transcribed the names of all persons bound for America from each of the fourteen lists. The emigrants, who are arranged alphabetically, are identified by place of origin and sometimes by the number of persons in the passenger's family or the names of traveling companions.
The Alterman Gambit Guide
The Alterman Gambit Guide: White Gambits is both an opening book and an instructive manual. Sharpen your tactics and learn to play dynamic attacking chess while studying the most entertaining gambits. Lines covered include: Evans Gambit Panov Attack Morra Gambit Philidor Danish Gambit Urusov Gambit Morphy Attack Cochrane Gambit Max Lange Attack Fried Liver Attack Milner-Barry Gambit Boris Alterman is a strong grandmaster and founder of the Shevah-Mofet Chess Academy in Israel. Alterman is a product of the Botvinnik-Kasparov chess school. He helped to develop the Deep Junior program which famously drew a match with Kasparov and defeated both Radjabov and Deep Fritz.
The Psychology of Language
This comprehensive study of the psychology of language explores how we speak, read, remember, learn and understand language. The author examines each of these aspects in detail.
Primate Conservation Biology
From the snub-nosed monkeys of China to the mountain gorillas of central Africa, our closest nonhuman relatives are in critical danger worldwide. A recent report, for example, warns that nearly 20 percent of the world's primates may go extinct within the next ten or twenty years. In this book Guy Cowlishaw and Robin Dunbar integrate cutting-edge theoretical advances with practical management priorities to give scientists and policymakers the tools they need to help keep these species from disappearing forever. Primate Conservation Biology begins with detailed overviews of the diversity, life history, ecology, and behavior of primates and the ways these factors influence primate abundance and distribution. Cowlishaw and Dunbar then discuss the factors that put primates at the greatest risk of extinction, especially habitat disturbance and hunting. The remaining chapters present a comprehensive review of conservation strategies and management practices, highlighting the key issues that must be addressed to protect primates for the future.
Cosmic Plasmas and Electromagnetic Phenomena
During the past few decades, plasma science has witnessed a great growth in laboratory studies, in simulations, and in space. Plasma is the most common phase of ordinary matter in the universe. It is a state in which ionized matter (even as low as 1%) becomes highly electrically conductive. As such, long-range electric and magnetic fields dominate its behavior. Cosmic plasmas are mostly associated with stars, supernovae, pulsars and neutron stars, quasars and active galaxies at the vicinities of black holes (i.e., their jets and accretion disks). Cosmic plasma phenomena can be studied with different methods, such as laboratory experiments, astrophysical observations, and theoretical/computat...
