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This new edition provides an accessible guide to the commonest neurodegenerative diseases, outlining the main clinical features, treatment options and outcomes of the conditions most frequently encountered in clinical practice. Beginning with an overview of the general principles that underlie degeneration, and the contribution of established and new diagnostics techniques, the book goes on to describe the most common neurodegenerative conditions and, new for the second edition, also HIV dementia and multiple sclerosis. Final chapters cover important management issues including the use of palliative care strategies, biomarkers and neuropsychology. Written by experts in the field internationally Neurodegenerative Disorders, Second Edition is a practical guide for clinicians that will be indispensable for the management of these conditions.
From 2000 to 2012 the number of Internet users rose from less than 0.4 billion to 2.4 billion. Scholarly, evidence-based Internet research is of critical importance. The field of Internet research explores the Internet as a social, political and educational phenomenon, providing theoretical and practical contributions to understanding, and informing practice, policy and further research. This new collection is a unique and welcome work. The editors have compiled a diverse range of new scholarly, peer-reviewed research, spanning the fields of education, arts, the social sciences and technology. The authors provide academic perspectives, both theoretical and practical, on the Internet and citi...
Humans are at a unique crossroads: never before have we had such a clear understanding of how our actions affect a changing climate, or how our settlement patterns along coastal environments put us at risk of rising sea levels. However, the science behind climate change (and solutions for it) are engulfed in political controversy. Dr. Christensen uses anthropological methods to illuminate the lived experience of families caring for elder relatives during climate related events: a unique conundrum facing increasing numbers of people living in coastal areas. As populations in industrialized countries grow older, they become more vulnerable to climate extremes. People over 65 are more likely to...
Inflammation has invaded the field of psychiatry. The finding that cytokines are elevated in various affective and psychotic disorders brings to the forefront the necessity of identifying the precise research domain criteria (RDoCs) that inflammation is responsible for. This task is certainly the most advanced in major depressive disorders. The reason is that a dearth of clinical and preclinical studies has demonstrated that inflammation can cause symptoms of depression and conversely, cytokine antagonists can attenuate symptoms of depression in medical and psychiatric patients with chronic low grade inflammation. Important knowledge has been gained on the symptom dimensions that inflammation is driving and the mechanisms of action of cytokines in the brain, providing new targets for drug research and development. The aim of the book “Inflammation-Associated Depression” is to present this field of research and its implications in a didactic and comprehensive manner to basic and clinical scientists, psychiatrists, physicians, and students at the graduate level.
Their women come from troubled packs that won’t let them leave... not until these shifters get involved. Hayden’s Haven (outcast, found family, tortured soul) Traitor. Outcast. Predator. That’s what they call him from the shadows. And they’re right. He’s all of those… and much more. Hayden will do anything to protect Mila, even challenge his former alpha, the brother who cast him out years ago. Frank’s Felon (grumpy sunshine, redemption, avoid commitment) Delilah’s tainted, targeted, far from tamed. And Frank wants her, badly. She’s his future, though she won’t admit it. He won’t let her enemies take her, even if it means starting a war with the humans. Mason’s Mission (forbidden love, rejected mate, secrets) Takara’s the enemy, born on the wrong side of the border. Despite how her pack abuses her, she refuses to defect to Mason’s pack because doing so will mean war between their packs and risk something greater than her and Mason’s love for one another. ◆◆◆ This collection includes three full-length novels that include danger, steamy sex, a lot of emotion, and several twists. Each ends in a Happy Ever After.
The sixth book in the critically acclaimed DI Marjory Fleming series. 'A welcome return for Templeton's tough but tender DI, Marjory 'Big Marge' Fleming... The vivid characterisation, excellent description and a horribly looming sense of inevitability make Cradle to Grave a riveting read.' Laura Wilson, Guardian 'Templeton can always be relied on to provide a well-written, cleverly-plotted, old-fashioned whodunit.' The Times Accused of murdering the baby in her care, seemingly cold and measured nanny Lisa Stewart maintains her innocence. But when she changes her name and tries to run away, the terrifying threats always find her. Is she an innocent victim of public anger? Or a calculating murderer on the run?
Published on the occasion of the exhibition Damien Hirst, Tate Modern, 4 April - 9 September 2012.
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Debrett's Peerage & Baronetage is the only up-to-date printed reference guide to the United Kingdom's titled families: the hereditary peers, life peers and peeresses, and baronets, and their descendants who form the fascinating tapestry of the peerage. This is the first ebook edition of Debrett's Peerage &Baronetage, and it also contains information relating to:The Royal FamilyCoats of ArmsPrincipal British Commonwealth OrdersCourtesy titlesForms of addressExtinct, dormant, abeyant and disclaimed titles.Special features for this anniversary edition include:The Roll of Honour, 1920: a list of the 3,150 people whose names appeared in the volume who were killed in action or died as a result of injuries sustained during the First World War.A number of specially commissioned articles, including an account of John Debrett's life and the early history of Debrett's Peerage and Baronetage, a history of the royal dukedoms, and an in-depth feature exploring the implications of modern legislation and mores on the ancient traditions of succession.
A lushly illustrated, magisterial exploration of the imaginative truth of the gospel In the modern academy, truth and imagination are thought to be mutually exclusive. But what if truth can spring from other fonts, like art, literature, and invention? The legacy of the Enlightenment favors historical and empirical inquiry above all other methods for searching for truth. But this assumption stymies our theological explorations. Though the historicity of Jesus’s life, death, and resurrection is important, it is not of sole importance. For instance, is John’s Gospel any less “true” than the Synoptics just because it’s less historically accurate? David Brown challenges us to expand our understanding of the gospel past source criticism and historical Jesus studies to include works of imagination. Reading Scripture in tandem with works of art throughout the centuries, Brown reenvisions the gospel as an open text. Scholars of theology and biblical studies, freed from literalism, will find new avenues of revelation in Gospel as Work of Art. This volume includes over one hundred color illustrations.