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Perez and Brady's Principles and Practice of Radiation Oncology
The thoroughly updated fifth edition of this landmark work has been extensively revised to better represent the rapidly changing field of radiation oncology and to provide an understanding of the many aspects of radiation oncology. This edition places greater emphasis on use of radiation treatment in palliative and supportive care as well as therapy.
Interdisciplinary management of central nervous system metastasis and neoplastic meningitis: recent developments and future perspectives
The incidence of metastatic disease in the central nervous system (CNS) is rising. According to current estimates, up to a third of adult cancer patients will suffer from CNS metastasis. Clinical evidence-based data from prospective randomized trials are rare, however, because CNS metastasis patients were often excluded from clinical trial participation. The management of CNS metastasis patients is therefore rather ill-defined and an interdisciplinary challenge. Recent basic and translational science data have begun contributing to a more profound understanding of the molecular mechanisms leading to invasion of tumor cells into the CNS. This report reviews advances, challenges, and perspectives in this field.
The Impact of Tumor Biology on Cancer Treatment and Multidisciplinary Strategies
Te rapidly changing concepts in radiation oncology with the development of more precise - strumentation for delivery of radiation therapy and a greater emphasis on hypofractionation technologies require a very intimate knowledge of tumor biology and the infuence of various biologic factors on dose distribution within the tumor in terms of homogeneity as well as prev- tion of any late efects on normal tissue surrounding the tumor itself. Not only are these major factors in clinical practice but also the known factors of inhomogeneity of cancer cells, the impact of microenvironment in terms of radiation efect, and host factors make it mandatory to design therapeutic strategies to improve the o...
Advances in Radiation Therapy
Developments in radiation oncology have been key to the tremendous progress made in the field in recent years. The combination of optimal systemic treatment and local therapy has resulted in continuing improved outcomes of cancer therapy. This progress forms the basis for current pre-clinical and clinical research which will strengthen the position of radiation oncology as an essential component of oncological care. This book summarizes recent advances in radiotherapy research and clinical patient care. Topics include radiobiology, radiotherapy technology, and particle therapy. Chapters cover a summary and analysis of recent developments in the search for biomarkers for precision radiotherapy, novel imaging possibilities and treatment planning, and advances in understanding the differences between photon and particle radiotherapy. Advances in Radiation Therapy is an invaluable source of information for scientists and clinicians working in the field of radiation oncology. It is also a relevant resource for those interested in the broad topic of radiotherapy in general.
Root Beer Candy and Other Miracles
Eleven-year-old Bailey believes in miracles. She has to; it will take a miracle to keep her warring parents together. This summer they are at a Marriage Counselling camp, leaving Bailey and her little brother Kevin with their estranged grandmother in the island town of Felicity Bay. There, an eccentric deposed minister makes a prophecy that a stranger from the sea will change everything. When Bailey discovers a mermaid-shaped piece of driftwood, she begins to believe that the mermaid is this stranger from the sea. Then, when a dolphin becomes stranded on the beach, Bailey forgets her own troubles and rouses the reluctant locals into action. Written in light and lyrical free verse, Shari Green’s warm and wistful novel brings Bailey face to face with both hard and beautiful truths about growing up and growing into her own ability to shape the world.
Combinatorial Approaches to Enhance Anti-Tumor Immunity: Focus on Immune Checkpoint Blockade Therapy
The immune system harbors great potential for controlling and eliminating tumors. Recent developments in the field of immuno-oncology has led to unprecedented clinical benefits for a broad spectrum of solid tumors. However, immunotherapy (IT) approaches currently have several limitations including (i) low response rate; (ii) development of resistance and (iii) causing severe immune-related adverse effects (IrAEs), which underline the importance of adequate patient selection. Importantly, IT holds promising synergistic potential when combined with standard-of-care chemotherapy, radiotherapy (RT) and anti-angiogenic therapy (AAT) as part of multi-modal oncologic treatment regimes. Published da...
KI 2011: Advances in Artificial Intelligence
This book constitutes the refereed proceedings of the 34th Annual German Conference on Artificial Intelligence, KI 2011, held in Berlin, Germany, in October 2011. The 32 revised full papers presented together with 3 invited talks were carefully reviewed and selected from 81 submissions. The papers are divided in topical sections on computational learning and datamining, knowledge representation and reasonings, augmented reality, swarm intelligence; and planning and scheduling.
