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This book provides comprehensive coverage of all aspects related to pediatric sleep and its associated disorders. It addresses the ontogeny and maturational aspects of physiological sleep and circadian rhythms, as well as the effects of sleep on the various organ systems as a function of development. Organized into nine sections, the book begins with a basic introduction to sleep, and proceeds into an extensive coverage of normative sleep and functional homeostasis. Part three then concisely examines the humoral and developmental aspects of sleep, namely the emerging role of metabolic tissue and the intestinal microbiota in regulation. Parts four, five, and six discuss diagnoses methods, tec...
Bringing together top-level contributions on all aspects of the subject, this book provides an overview of the recent advances in the genetics of respiratory control in health and disease. It also shows how combined studies in humans and mouse models have helped to improve our understanding of the mechanisms that underlie genetically determined respiratory control disorders with the goal of developing new therapeutic interventions.
Sleep Disordered Breathing in Children: A Comprehensive Clinical Guide to Evaluation and Treatment is a comprehensive, timely and up-to-date review of pediatric sleep disordered breathing (SDB) and offers a thorough focus on several key areas: namely, the normal development and maturation of the airway and breathing during sleep, the techniques that are in place for assessment of SDB in children, the clinical manifestations and characteristics of several pediatric populations at risk for SDB, the implications of SDB in various end-organ systems, and, finally, a critical review of the evidence on current therapeutic approaches. This unique and complete text is of welcome interest to all pract...
Obstructive sleep apnoea (OSA) is a common and progressive chronic disease. It is responsible for a high number of comorbidities and is linked with increased mortality, including a rise in the rate of sudden cardiac death. It is widely acknowledged that OSA now affects millions of people worldwide. This Monograph considers this high-impact condition from four different perspectives: pathogenesis; at-risk populations; clinical scenarios; and treatment and management. Comprehensive and up-to-date chapters provide the reader with a concise overview of OSA, making this book a useful reference for pulmonologists concerned with the management of this disease.
This definitive text on respiratory disease in children has been completely updated and revised for the 7th Edition. Several new chapters have been added, including information on the impact of environmental pollution on lung disease in children. Provides the most authoritative and comprehensive coverage available of basic science and clinical problems related to pediatric lung disease.
Sleep Science is a broad, advanced introduction to the subject of sleep and sleep disorders. Each chapter follows a consistent layout and is authored by a subject matter expert who also teaches undergraduate students in the classroom and/or mentors these students in their sleep laboratory.
Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep...
This second edition of the landmark 1991 text, Basic Mechanisms of Pediatric Respiratory Disease reviews the importance of the integrations of molecular, cellular and physiologic strategies in the development of a new understanding of pediatric respiratory disorders. It provides state-of-the-art information about fundamental mechanisms underlying ......
Easy to read and richly illustrated, Atlas of Clinical Sleep Medicine, 3rd Edition, provides the tools you need to accurately diagnose and treat the full range of adult and pediatric sleep disorders. Dr. Meir H. Kryger and a team of expert contributing authors detail the physiologic, clinical, morphologic, and investigational aspects of the sleep disorders you encounter in everyday practice—enhanced by high-quality images throughout. This highly regarded, award-winning atlas is an ideal resource for sleep practitioners and technicians in the lab, as well as an effective review for certification and recertification. - Features a thoroughly illustrated, reader-friendly format that highlights...
The book describes the mechanisms involved in the maintenance of neuroendocrine-immune interactions in ageing. The lack of this maintenance leads to the appearance of age-related diseases (cancer, infections, dementia) and subsequent disability. The capacity of some hormones or nutritional factors in restoring and remodelling the neuroendocrine-immune response during ageing is reported presenting possible new anti-ageing strategies in order to reach healthy ageing and longevity