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Authored by renowned leaders in the field, this comprehensive volume covers all aspects of drug-drug interactions, including preclinical, clinical, toxicological, and regulatory perspectives.Thoroughly updated, this second edition reflects the significant advances and includes extensive new material on:key interplay between transporters and enzymes
Applies recent molecular discoveries to the evolving treatment of skin therapy and points out future research areas. Presenting the most up-to-date research in wound treatment, this comprehensive reference analyzes the critical alterations in the composition and organization of the extracellular matrix following injury. Beginning with a chem
This book approaches the problematic of social exclusion by way of the analysis of the symbiotic pair social exclusion/social inclusion. Its main concern is the problematisation of this pair in different contexts (both social, cultural and educational and at the local, national and supranational levels) through an analysis of five of the sites - body, work, citizenship, identity and territory - upon which social exclusion/inclusion makes its impact. Thus, an inductive approach to theories on social exclusion (and social inclusion) is developed through the study of their real effects on individuals, groups and society on the basis of three socio-cultural paradigms, namely, traditional societi...
Germination of the thought of "Enzymatic- and Transporter-Based Drug-Drug Interactions: Progress and Future Challenges" Proceedings came about as part of the annual meeting of The American Association of Pharmaceutical Scientists (AAPS) that was held in San Diego in November of 2007. The attendance of workshop by more than 250 pharmaceutical scientists reflected the increased interest in the area of drug-drug interactions (DDIs), the greater focus of PhRMA, academia, and regulatory agencies, and the rapid pace of growth in knowledge. One of the aims of the workshop was to address the progress made in quantitatively predicting enzyme- and transporter-based DDIs as well as highlighted areas wh...
This e-book tells the story of a fantastic and epic adventure, which takes place in a scenario based on the universe of the famous role-playing game (Dungeons & Dragons). When a great threat arises, a group of heroes need to find the only ally who can help them save the world, but to do so they need to begin a dangerous, surprising and magical journey that tests their strength, courage, determination, hope. and bonds of friendship. This book is illustrated and presents the heroes and striking scenes of the narrative in detailed illustrations and rich in details. If you like medieval fantasy stories or if you know the game (Dungeons & Dragons) you will identify a lot with this story of heroism that will surprise you from the first page to the last, which could even serve as inspiration for a D&D campaign.
This book addresses both domestic and foreign readers, and for that reason appears in English. Following the survey of history of the Lisbon Exchange published in 1996 by David Justino, the present text extends that medieval period to the Nineteenth century analysis to the present day. Many other Stock Exchanges in Europe and elsewhere have been studied and published by many authors, but no comparable book for Portugal has existed until the present work. The text is accessible to medium-knowledge readers. In a world of internationalization of corporations and financial institutions it is paramount that they be able to mobilize the capacities of the Capital Market to finance the economy, and ...