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Adaptive Oncogenesis
Popular understanding holds that genetic changes create cancer. James DeGregori uses evolutionary principles to propose a new way of thinking about cancerÕs occurrence. Cancer is as much a disease of evolution as it is of mutation, one in which mutated cells outcompete healthy cells in the ecosystem of the bodyÕs tissues. His theory ties cancerÕs progression, or lack thereof, to evolved strategies to maximize reproductive success. Through natural selection, humans evolved genetic programs to maintain bodily health for as long as necessary to increase the odds of passing on our genesÑbut not much longer. These mechanisms engender a tissue environment that favors normal stem cells over pre...
Shining and Other Paths
The first comprehensive study of the Shining Path, the Maoist sect of indigenous people who waged a a brutal war in Peru during the 1980s and early 1990s in an attempt to effect a Communist revolution .
Good Enough
In this spirited and irreverent critique of Darwin’s long hold over our imagination, a distinguished philosopher of science makes the case that, in culture as well as nature, not only the fittest survive: the world is full of the “good enough” that persist too. Why is the genome of a salamander forty times larger than that of a human? Why does the avocado tree produce a million flowers and only a hundred fruits? Why, in short, is there so much waste in nature? In this lively and wide-ranging meditation on the curious accidents and unexpected detours on the path of life, Daniel Milo argues that we ask these questions because we’ve embraced a faulty conception of how evolution—and hu...
Proteomics
Biomedical research has entered a new era of characterizing a disease or a protein on a global scale. In the post-genomic era, Proteomics now plays an increasingly important role in dissecting molecular functions of proteins and discovering biomarkers in human diseases. Mass spectrometry, two-dimensional gel electrophoresis, and high-density antibody and protein arrays are some of the most commonly used methods in the Proteomics field. This book covers four important and diverse areas of current proteomic research: Proteomic Discovery of Disease Biomarkers, Proteomic Analysis of Protein Functions, Proteomic Approaches to Dissecting Disease Processes, and Organelles and Secretome Proteomics. We believe that clinicians, students and laboratory researchers who are interested in Proteomics and its applications in the biomedical field will find this book useful and enlightening. The use of proteomic methods in studying proteins in various human diseases has become an essential part of biomedical research.
The Woman that Never Evolved
The author dispels some of the myths about the nature of females and female sexuality, and suggests new hypotheses aboutthe evolution of women.
Lucy's Legacy
Takes a look at human evolution focusing on the long line of women and of female behavior that was to follow the age of the much-studied oldest human remains.
Evolution, Games, and God
According to the reigning competition-driven model of evolution, selfish behaviors that maximize an organism’s reproductive potential offer a fitness advantage over self-sacrificing behaviors—rendering unselfish behavior for the sake of others a mystery that requires extra explanation. Evolution, Games, and God addresses this conundrum by exploring how cooperation, working alongside mutation and natural selection, plays a critical role in populations from microbes to human societies. Inheriting a tendency to cooperate, argue the contributors to this book, may be as beneficial as the self-preserving instincts usually thought to be decisive in evolutionary dynamics. Assembling experts in m...
Subaltern Geographies
Subaltern Geographies explores the intersection between subaltern studies and cultural, urban, historical, and political geography to unravel subaltern perspectives, acknowledging the intricacies involved in conceiving and representing these spaces.
The Peru Reader
Sixteenth-century Spanish soldiers described Peru as a land filled with gold and silver, a place of untold wealth. Nineteenth-century travelers wrote of soaring Andean peaks plunging into luxuriant Amazonian canyons of orchids, pythons, and jaguars. The early-twentieth-century American adventurer Hiram Bingham told of the raging rivers and the wild jungles he traversed on his way to rediscovering the “Lost City of the Incas,” Machu Picchu. Seventy years later, news crews from ABC and CBS traveled to Peru to report on merciless terrorists, starving peasants, and Colombian drug runners in the “white gold” rush of the coca trade. As often as not, Peru has been portrayed in broad extreme...
