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Advances in Cancer Research
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics.
Cell Lineage Choice During Haematopoiesis: A Commemorative Issue in Honor of Professor Antonius Rolink
This book is a printed edition of the Special Issue "Cell Lineage Choice During Haematopoiesis: A Commemorative Issue in Honor of Professor Antonius Rolink" that was published in IJMS.
AACR 2017 Proceedings: Abstracts 1-3062
The AACR Annual Meeting highlights the best cancer science and medicine from institutions all over the world. Attendees are invited to stretch their boundaries, form collaborations, attend sessions outside their own areas of expertise, and learn how to apply exciting new concepts, tools, and techniques to their own research. Part A contains abstracts 1-3062 accepted for the 2017 meeting.
Metabolic Barriers in Cancer and Cancer Therapy
Cancer immunometabolism is an emerging field exploring cellular bioenergetic alterations in both tumor and immune cells and their impact on tumor immune surveillance and therapy resistance. Multiple concepts have emerged including metabolic competition over nutrients and the secretion of (toxic) metabolic byproducts by cancer cells. Moreover, cancer cells are capable of utilizing and shaping their surrounding microenvironment to their favor, e.g. by reprogramming stroma cells to produce essential nutrients or by providing metabolically relevant signaling molecules to foster the accumulation of immunosuppressive cells. Most importantly, this crosstalk within the tumor microenvironment is mostly multi-directional and a better understanding of the complex interactions may pave the way to improved and/or novel therapeutic strategies to overcome those obstacles.
