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Lung cancer continues to be the leading cause of cancer mortality worldwide among both men and women. Recent advances in prevention, screening and management in the past decade have led to significant improvements in survival and quality of life. Local treatments like minimally invasive surgery, radiotherapy, and image-guided ablation have contributed to improving the effectiveness and tolerability of potentially curative treatments in early-stage, locally advanced, and oligometastatic/oligoprogressive disease. Chemotherapy, targeted therapy, immunotherapy, and palliative local therapy options have expanded rapidly, with new regimens showing improved outcomes even for those with widely metastatic disease. This book comprehensively reviews the evidence that has driven personalized medicine, based on a variety of multidisciplinary perspectives by international lung cancer experts.
The International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications (MAVEBA) came into being in 1999 from the particularly felt need of sharing know-how, objectives and results between areas that until then seemed quite distinct such as bioengineering, medicine and singing. MAVEBA deals with all aspects concerning the study of the human voice with applications ranging from the newborn to the adult and elderly. Over the years the initial issues have grown and spread also in other fields of research such as occupational voice disorders, neurology, rehabilitation, image and video analysis. MAVEBA takes place every two years in Firenze, Italy. This edition celebrates twenty-two years of uninterrupted and successful research in the field of voice analysis.
Modern Radiotherapy (RT) plays a key role in the management of Head and Neck Cancer (HNC). More precise delivery techniques, advanced image-guidance, and adaptive treatments characterize modern RT, enabling safer treatments with enhanced therapeutic window. Although patients identify the cure as their most important treatment outcome, complications related to treatment are a recognized problem as follow-up increases among those cured within this oncologic setting. This is particularly relevant for HPV-related oropharyngeal cancer (OPSCC), as these patients are younger, healthier, and more reactive to treatment. Thus, given the longer life expectancy, the jeopardizing impact of side effects on quality of life (QoL) and psychosocial functioning represent a forefront topic for HNC Researchers. De-escalation protocols have been developed recently, and, although not definitive, evidence is growing. This pertains particularly, but not exclusively, to HPV-related OPSCC.
This book constitutes the refereed proceedings of the 9th Conference on Artificial Intelligence in Medicine in Europe, AIME 2003, held in Protaras, Cyprus, in October 2003. The 24 revised full papers and 26 revised short papers presented together with two invited contributions were carefully reviewed and selected from 65 submissions. The papers are organized in topical sections on temporal reasoning, ontology and terminology, image processing and simulation, guidelines and clinical protocols, terminology and natural language issues, machine learning, probabilistic networks and Bayesian models, case-based reasoning and decision support, and data mining and knowledge discovery.
This book constitutes the refereed proceedings of the 9th Conference on Artificial Intelligence in Medicine in Europe, AIME 2003, held in Protaras, Cyprus, in October 2003. The 24 revised full papers and 26 revised short papers presented together with two invited contributions were carefully reviewed and selected from 65 submissions. The papers are organized in topical sections on temporal reasoning, ontology and terminology, image processing and simulation, guidelines and clinical protocols, terminology and natural language issues, machine learning, probabilistic networks and Bayesian models, case-based reasoning and decision support, and data mining and knowledge discovery.
The book deals with the intricate challenges academia faces in integrating skill development into the curriculum and how improving the industry-academia interface could be a solution through education policies. It responds to the need for skill-centric development, aligning with the demands of Education 4.0 in today’s Industry 4.0. This multi-disciplinary volume covers the need for effective collaboration between education sectors and industries, covering the modern-day needs of the labour market and initiatives of the public sector. On the other hand, it emphasises the role of education policies, non-formal education and training for teachers in developing skills for different stakeholder...
Financial Risk Measurement is a challenging task, because both the types of risk and the techniques evolve very quickly. This book collects a number of novel contributions to the measurement of financial risk, which address either non-fully explored risks or risk takers, and does so in a wide variety of empirical contexts.