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Impactful Times
This book presents a history of shock compression science, including development of experimental, material modeling, and hydrodynamics code technologies over the past six decades at Sandia National Laboratories. The book is organized into a discussion of major accomplishments by decade with over 900 references, followed by a unique collection of 45 personal recollections detailing the trials, tribulations, and successes of building a world-class organization in the field. It explains some of the challenges researchers faced and the gratification they experienced when a discovery was made. Several visionary researchers made pioneering advances that integrated these three technologies into a c...
Clinical Virology
Informs scientists and health care professionals about all the medically relevant aspects of this rapidly evolving field. • Covers novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention. • Addresses infections and syndromes related to particular organ systems, as well as the fundamentals of modern medical virology. • Includes crucial information on immune responses and vaccinology, diagnostics, antivirals, and the nascent field of gene therapy. • Provides agent-specific chapters that detail the virology, epidemiology, pathogenesis, clinical manifestations, and prevention and treatment of important viral pathogens.
Comprehensive Natural Products II
This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas am...
Classification and Nomenclature of Viruses
The Fifth Report of the International Committee on Taxonomy of Viruses (ICTV), summarizes the proceedings and decisions reached by the ICTV at its meetings held at the International Congresses of Virology in Sendai (1984), Edmonton (1987) and Berlin (1990). This report has been organized in the same way as the previous ones (Wildy, 1971; Fenner, 1976; Matthews, 1979; 1982), yet it encompasses many more families and groups of viruses than previous reports, and it includes new tables, diagrams and keys. The officers and members of the ICTV study groups from 1984 to 1990 are listed, as the current ICTV statutes and rules of nomenclature. Information on the format for submission of new taxonomic...
High-Pressure Shock Compression of Solids VIII
Research in the field of shock physics and ballistic impact has always been intimately tied to progress in development of facilities for accelerating projectiles to high velocity and instrumentation for recording impact phenomena. The chapters of this book, written by leading US and European experts, cover a broad range of topics and address researchers concerned with questions of material behaviour under impulsive loading and the equations of state of matter, as well as the design of suitable instrumentation such as gas guns and high-speed diagnostics. Applications include high-speed impact dynamics, the inner composition of planets, syntheses of new materials and materials processing. Among the more technologically oriented applications treated is the testing of the flight characteristics of aeroballistic models and the assessment of impacts in the aerospace industry.
The Evolutionary Biology of Flies
Flies (Dipteria) have had an important role in deepening scientists'understanding of modern biology and evolution. The study of flies has figured prominently in major advances in the fields of molecular evolution, physiology, genetics, phylogenetics, and ecology over the last century. This volume, with contributions from top scientists and scholars in the field, brings together diverse aspects of research and will be essential reading for entomologists and fly researchers.
Bluetongue, African Horse Sickness, and Related Orbiviruses
Bluetongue, African Horse Sickness, and Related Orbiviruses: Proceedings of the Second International Symposium provides the latest scientific information about this group of Orbiviruses, which are transmitted by species of Culicoides (biting midges) and are important causes of disease in domestic livestock and wildlife. Originally presented at the Second International Symposium on the Orbivirus held in Paris, France in June 1991, the book reviews the history and latest data on epizootiology; clinical syndromes and host responses; vector biology, competence, genetics, and capacity; molecular virology and genetics; and diagnostic procedures. The book covers regulatory issues associated with bl...
Protocols for Cytogenetic Mapping of Arthropod Genomes
Arthropods are important to worldwide agriculture, food safety, human health, and energy production. Besides their practical significance, various species represent excellent model systems for biological investigations of evolution, development, physiology, reproduction, and social interaction. For these reasons, arthropod genomics is receiving increasing attention from researchers around the globe. Protocols for Cytogenetic Mapping of Arthropod Genomes is a collection of up-to-date, detailed protocols for physical chromosome mapping and their applications for studying genome organization and evolution in insects and ticks. This book brings together the expertise of cytogeneticists working o...
Understanding Tuberculosis
In 1957, a Streptomyces strain, the ME/83 (S.mediterranei), was isolated in the Lepetit Research Laboratories from a soil sample collected at a pine arboretum near Saint Raphael, France. This drug was the base for the chemotherapy with Streptomicine. The euphoria generated by the success of this regimen lead to the idea that TB eradication would be possible by the year 2000. Thus, any further drug development against TB was stopped. Unfortunately, the lack of an accurate administration of these drugs originated the irruption of the drug resistance in Mycobacterium tuberculosis. Once the global emergency was declared in 1993, seeking out new drugs became urgent. In this book, diverse authors focus on the development and the activity of the new drug families.
