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Developmental Coaching
Coaches often say that their coaching is developmental, but what they mean by this varies significantly. This groundbreaking book introduces a new theory of developmental coaching and a new framework for coaching practice. It explores the most puzzling and debated aspects of human nature, such as 'self', 'free will' and 'psychological evolution' - and then introduces both a new theory of developmental coaching and a new framework for coaching practice. Tatiana Bachkirova addresses highly debated and complex ideas with ease and explains their relevance to everyday living and helping people to move forward in their lives. To make these ideas real for coaches the book is written in a clear and engaging way with examples, illustrations, exercises and case studies. Coaches who wish to enrich their practice will find plenty to learn, reflect on and apply immediately in their client engagements. Coaches who see their own self as a crucial element of a coaching encounter will have an opportunity to explore and enhance their own developmental process. Students of advanced coaching programmes will find this book both intellectually stimulating and a useful resource for practice.
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Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
