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Anabolic Steroids attempts to trace the development of anabolic steroids in the chemical, experimental biological, and clinical disciplines, and presents a precise outline of the current state of substantiated knowledge. This book deals with anabolic steroids derived from natural androgens and characterized by their stimulatory action on the biosynthesis of tissue protein and by their simultaneous low androgenicity. The biochemical part is a review of substantiated and current knowledge based largely on experimental results with animals, while the clinical part attempts to bring out the pathophysiological rationale of therapy with anabolic steroids, again based on experimental data. The book begins with a discussion of the nomenclature and chemistry of anabolic steroids. This is followed by separate chapters on the metabolism, activities, and mechanism of action of anabolic steroids; clinical application of anabolic steroids, side effects, and test procedures.
connective tissues are essential for the physical functioning of the animals's body. The condition of the various connective tissues is governed by biochemical factors, anabolism and catabolism, that are controlled by specific enzymes. Any change outside the normal range of metabolism, for instance induced by immunological reactions, may induce a pathological disturbance. The result can be acute or chronic inflammation, or loss of normal function, expressed in loosening, dilatation, breaking, wear, stiffness, shrinking, scars, stenosis, and cirrhosis or any other kind of fibrosis. A first step toward improving our understanding of the feedback mecha nism that maintains the biological status ...
Covers neurophysioligcal and psychological effects of alcohol on man. Includes extensive bibliographies covering the literature from 1920 through 1970.
This book continues the series of reviews of research advances first published in 1974. The editors' aim here is to present critical and integrative reviews by internationally recognized scholars of areas in which there has been much recent research. In this task we have been greatly helped by the staff of Plenum Press and the Advisory Panel listed at the front of this volume. Several members of the Panel have retired: Dr. W.M.D. Paton, Dr. K. Bruun, Dr. K.F. Killam, and Dr. J .R. Seeley. Dr. Klaus Makela has accepted our invitation to join the Panel. Unfortunately, one member of the Panel, Professor William McGlothlin, died as a result of a tragic accident. He was a gifted and sensitive res...