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The dramatic advances in molecular genetics are becoming incorporated into neurobiologic studies at an ever increasing rate. In developmental neurobiology, the importance of cell cell interactions for neurogenesis and gene expression is be ginning to be understood in terms of the molecular bases for these interactions. This book seeks to emphasize the importance of molecular technology in the study of neurogenetic mechanisms and to explore the possible relationships between specific cell cell interactions and regulated gene expression in the develop ing nervous ~stem. This volume consists of nineteen chapters which address ques tions of gene expression and the importance of cell-cell interac...
This unique book by leading experts reviews the key therapeutic issues related to stem cell technology.
Proteins, Cells and Materials contains a collection of articles, which constitute together the complete Festschrift in honor of the 65th birthday of Dr. John L. Brash. For the first time these articles - published previously in several special issues of the Journal of Biomaterials Science Polymer Edition - have been compiled into one comprehensive volume.Over the past 40 years John Brash, a member of the Editorial Board of the Journal of Biomaterials Science Polymer Edition, has distinguished himself in the field of biomaterials. Much of his efforts have focused on detailed studies of blood–surface interactions, particularly those of plasma proteins. His multi-faceted approach recognises the importance of hemodynamics, transport and surface phenomena in the gross effects that result from blood–surface contact. In this book articles on the most recent development in these areas are collected and will thus provide a wealth of information of current research to specialists in the above-mentioned fields.
Work in the area of biomaterials and stem cell therapy has revealed great potential for many applications, from the treatment of localized defects and diseases to the repair and replacement of whole organs. Researchers have also begun to develop a better understanding of the cellular environment needed for optimal tissue repair and regeneration. Biomaterials and Stem Cells in Regenerative Medicine explores a range of applications for biomaterials and stem cell therapy and describes recent research on suitable cell scaffolds and substrates for tissue repair and reconstruction. Featuring contributions by experts in the field, the book explores important scientific and clinical aspects. It cove...
Annotation. Stem Cells and Regenerative Medicine, Volumes I, II, and III, present an overview and in-depth analysis of recent developments in stem cell research and therapy in a compilation of recently-published, peer-reviewed articles.
''Interesting with many useful ideas and references. It covers a broad range and it is a good introduction to this field.'' ---Analyst
This two-volume work contains the full text of the oral and poster presentations and the general discussion at the round table discussion of the Second International Conference on Alzheimer's and Parkinson's Diseases: Basic and Therapeutic Strategies, held at the Kyoto Park Hotel in Kyoto, Japan, on November 6-10, 1989. The First Conference was held at the Aviya Sonesta Hotel in Eilat, Israel, on March 24-27, 1985. The record of this First Conference was published by Plenum Press in 1986 as Volume 29 in Advances in Behavioral Biology, under the title "Alzheimer's and Parkinson's Diseases: Strategies for Research and Development." We are happy that the comprehensive texts of the oral and post...
"Details the function, characterization, and physiology of various dopamine receptor/transporter systems and explores their role in etiology, diagnosis, and disease management."
The last decades have witnessed a radical change in our views on central nervous system damage and repair. This change is not only due to the emergence of new powerful tools for the analysis of the brain and its reactions to insults, but it also reflects a conceptual change in the way we approach these problems. As an illustration to this development, it is instructive to go back to the proceedings of a meeting at the NIH in 1955 edited by William F. Windle, which summarizes the disillusioned and pessimistic view on CNS regeneration prevailing at the time. While this generation of researchers were well aware of the issues at stake, they felt they had reached the end of the road; the approaches they had pursued had got stuck and the tools available could not take them any further. I can very well imagine that the participants, most of them leaders in the field, left that conference feeling they had heard their field being sentenced to death.
This book represents the coming together of a number of internationally renowned scholars from science, philosophy, law and social science. Each author presents a distinctive and critical account of the current ethical, social and jurisprudential issues concerning stem cell science: together covering both its research beginnings, and the future translation into the clinical setting. Original to this volume is an emphasis on the inter-state implications of developments in stem cell science from the perspective of a truly global collaboration of leading authors. Academics and policy-makers will find it an invaluable contribution to the socio-political and ethical discourse of stem cell science./a