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Stroke is a leading cause of death and the major cause of long-term, physical, psychological and social disability in the elderly around the world. Knowing and treating the most common risk factors for stroke such as hypertension, diabetes mellitus, dyslipidemia, atrial fibrillation, and obesity may reduce the occurrence of stroke sub-stantially. In the last decades, there has been tremendous progress in the development of noninvasive diagnostic techniques like ultrasound MRI, CT angiography, CT perfusion, as well as new effective therapeutic strategies for acute ischemic stroke which established vascular neurology as one of the most progressive fields in medicine. This publication provides the reader with the most recent updated advanced knowl-edge on the practical clinical approach to stroke medicine. It covers essential and practical information on the pathophysiology and epidemiology of stroke, new diagnostic techniques which allow for better diagnosis and identification of various subtypes of stroke, and new therapeutic strategies for acute stroke and transient ischemic attack.
A practical handbook written for the practising physician 'Stroke Medicine' provides an up-to-date, and easily accessible source of information on all aspects of stroke care from acute care, through to rehabilitation and secondary prevention.
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Over the last decade there has been a substantial increase in our understanding of the genetic basis of common disorders such as stroke. Stroke Genetics is designed to give the reader an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics benefits from the contribution of renowned experts from throughout the world who have been intimately involved in unraveling the genetic etiology of stroke. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics.
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