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Highly Commended in the 2006 British Medical AssociationBook Awards (Endocrinology) This Second Edition brings together more than 20 internationallyrecognized experts in the field to provide a timely review ofcurrent knowledge. The text remains an invaluable resource for allhealthcare professionals involved in the care of patients who areobese. New features of this Second Edition include: Addition of two new co-editors – Professor Bill Dietz,USA and Professor Ian Caterson, Australia Increased number of contributors from around the globe –providing a truly international perspective Includes new information about the causes of obesity, itscomplications and new (and novel) methods of prevention andtreatment Reorganized into sections that address obesity and its socialand cultural aspects, biology, associated diseases, life stages(pediatric and adult), management, and environmental and policyapproaches
Discover new and emerging applications for microdialysis in drug evaluation Microdialysis is a highly valuable sampling tool that can be used in vivo to measure free, unbound analyte concentrations located in interstitial and extracellular spaces. This book explores the full range of clinical applications for microdialysis, focusing on its use in different organ and tissue systems for pharmacokinetic and pharmacodynamic studies. Readers gain a full understanding of the underlying science of microdialysis, current techniques and practices, as well as its many applications in pharmaceutical research. Applications of Microdialysis in Pharmaceutical Science starts with an introduction to basic p...
This comprehensive textbook addresses one of the major public health concerns of our era – obesity. Clearly and simply, Obesity: science to practice provides a balanced, coherent account of obesity: how to define and measure it, its epidemiology, the physiological basis, associated diseases, how to assess, manage and treat it, and also strategies for prevention. The book is generously illustrated, including graphs and flow charts for easy reference. The chapters cite key references so that interested readers may pursue a given topic in more detail. Well presented and thoroughly edited by one of the leading experts in the field, this is the textbook of choice for anyone working in obesity.
This book examines the practices of contesting evidence in democratically constituted knowledge societies. It provides a multifaceted view of the processes and conditions of evidence criticism and how they determine the dynamics of de- and re-stabilization of evidence. Evidence is an essential resource for establishing claims of validity, resolving conflicts, and legitimizing decisions. In recent times, however, evidence is being contested with increasing frequency. Such contestations vary in form and severity – from questioning the interpretation of data or the methodological soundness of studies to accusations of evidence fabrication. The contributors to this volume explore which actors,...