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Evolution and Development
The marriage of evolutionary biology with developmental biology has resulted in the formation of a new field, evolutionary developmental biology, or "evo-devo. This volume reviews current research findings and thought in the broad field of evo-devo, looking at the developmental genetic mechanisms that cause variation and how alterations of these mechanisms can generate novel structural changes in a variety of plant and animal life. - Reviews current research findings and thought on evolutionary developmental biology, providing researchers an overview and synthesis of the latest research findings and contemporary thought in the area - Includes chapters discussing the evolutionary development of a wide variety of organisms and allows researchers to compare and contrast how genes are expressed in a variety of organisms—from fly to frog, to humans - Emphasizes the role of regulatory DNA in evolutionary development to give researchers perspective on how the regions of the genome that control gene expression and the protein factors that bind them are ultimately responsible for the diversity of life that has evolved
Germ Cell Development in C. elegans
Germ cells in sexually reproducing metazoa, through the germline lineage, are the route by which genetic material and cytoplasmic constituents are passed from one generation to the next in the continuum of life. Chapters in this book review germ cell development in the model organism Caenorhabditis elegans, discussing the biology, the genetics and the molecular mechanisms for various processes, as well as drawing comparisons with other organisms. Processes discussed include specification of germ cell fate, meiosis, gametogenesis, environmental/ physiological controls, epigenetics and translational control, fertilization and the oocyte-to-embryo transition. This book thus provides a comprehensive picture of the germline lineage and the continuum of life for the worm.
Myogenesis
Myogenesis is the formation of muscular tissue, in particular during embryonic development. This new volume in the "Current topics in Developmental Biology" series covers chapters on such topics as Control of nuclear import during myogenesis, Pathways contributing to fibrosis in skeletal muscle, and Ferlin family members in myogenesis. With an international team of authors, this volume is a must-have addition for researchers and students alike. This new volume in the "Current topics in Developmental Biology" series covers chapters on such topics as Control of nuclear import during myogenesis, Pathways contributing to fibrosis in skeletal muscle, and Ferlin family members in myogenesis With an international team of authors, this volume is a must-have addition for researchers and students alike
Cancer and Development
In recent years, a number of molecular pathways and cellular processes that are essential for normal vertebrate development have been implicated in cancer initiation and progression. In this volume, leaders in the field of cancer genetics and developmental biology share recent insights into the importance of developmental pathways for tumorigenesis. These discoveries provide important avenues for innovative new approaches to treating some of the most challenging developmental tumors. - Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area - There are now a large number of molecular targeted therapies for the treatment of cancer. Many of these therapies target pathways that are essential for normal development. Therefore, this volume provides an up-to-date and timely perspective on those pathways and biological processes that hold the greatest promise for targeted intervention.
Plant Development
A subgroup of homeobox genes, which play an important role in the developmental processes of a variety of multicellular organisms, Hox genes have been shown to play a critical role in vertebrate pattern formation. Hox genes can be thought of as general purpose control genes—that is, they are similar in many organisms and direct the same processes in a variety of organisms, from mouse, to fly, to human. - Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area - Inclusion of chapters that discuss the evolutionary development of a wide variety of organisms - Gives researchers and clinicians insight into how defective Hox genes trigger developmental abnormalities in embryos
Forces and Tension in Development
This book presents some of the most advanced experimental systems in which the role of forces has been dissected. It explores the physical principles accounting for how forces can affect soft matter such as our cells, and presents some of the methods used to measure or assess the role of forces. - Presents some of the most advanced experimental systems in which the role of forces has been dissected - Explores the physical principles accounting for how forces can affect soft matter such as our cells, and presents some of the methods used to measure or assess the role of forces - Appeals to both physicists eager to get familiar with biological systems and to biologists curious about the physical principles behind what they observe
Heart Development
The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in heart disease. A stellar collection of scientists tackles an important facet of heart development, providing a comprehensive set of reviews. - Cutting-edge science - Authority of contributors - Exciting field of research
Evolutionary Theory
The natural world is infinitely complex and hierarchically structured, with smaller units forming the components of larger systems: genes are components genomes, cells are building blocks of tissues and organs, individuals are members of populations, which, in turn, are parts of species. In the face of such awe inspiring complexity, scientists need tools like the hierarchy theory of evolution, which provides a theoretical framework and an interdisciplinary research program that aims to understand the way complex biological systems work and evolve. The multidisciplinary approach looks at the structure of the myriad intricate interactions across levels of organization that range from molecules to the biosphere. Evolutionary Theory: A Hierarchical Perspective provides an introduction to the theory, which is currently driving a great deal of research in bioinformatics and evolutionary theory. Written by a diverse and renowned group of contributors, and edited by the founder of Hierachy Theory Niles Eldredge, this work will help make transparent the fundamental patterns driving living sytems.
Growth Factors in Development
This new volume of the renowned serial Current Topics in Developmental Biology covers the important features of growth factors in development. With an international board of authors, this volume will be invaluable for researchers in cell, developmental and molecular biology. Provides researchers an overview and synthesis of the latest research findings and contemporary thought in the area This volume provides an up-to-date and timely perspective
MicroRNAs in Development
This new volume in the Current topics in Developmental Biology series concentrates on MicroRNAs in Development. It includes chapters on such topics as miRNA networks in neuronal development, let-7 in development, and Hox networks and miRNA. With an international team of authors, this volume is a must-have addition for researchers and students alike. Concentrates on microRNAs in development Includes chapters on such topics as miRNA networks in neuronal development, let-7 in development, and Hox networks and miRNA With an international team of authors, this volume is a must-have addition for researchers and students alike
