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The introduction of anti-tumour necrosis factor (TNF) antibodies into the treatment of patients with IBD about fifteen years ago has dramatically improved the quality of life for patients with severe Crohn's disease and ulcerative colitis. But despite the fact this therapeutic approach has been around for quite some time, there has been no comprehensive overview to date. The book at hand aims to amend this shortcoming, presenting for the first time a thorough overview on TNF action, mechanisms of anti-TNF therapy, treatment strategies, side effects, monitoring, biosimilars and related issues. Including state-of-the-art information and research results, this publication will be a valuable source of information and guide clinicians to the optimal treatment decision, improving the quality of life of patients with inflammatory bowel disease. Moreover, rheumatologists or even dermatologists might also find this book of interest.
The Congressional Record is the official record of the proceedings and debates of the United States Congress. It is published daily when Congress is in session. The Congressional Record began publication in 1873. Debates for sessions prior to 1873 are recorded in The Debates and Proceedings in the Congress of the United States (1789-1824), the Register of Debates in Congress (1824-1837), and the Congressional Globe (1833-1873)
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Chronicles the Nazi's rise to power, conquest of Europe, and dramatic defeat at the hands of the Allies.
From 1940 to 1942, French secret agents arrested more than two thousand spies working for the Germans and executed several dozen of them—all despite the Vichy government’s declared collaboration with the Third Reich. A previously untold chapter in the history of World War II, this duplicitous activity is the gripping subject of The Hunt for Nazi Spies, a tautly narrated chronicle of the Vichy regime’s attempts to maintain sovereignty while supporting its Nazi occupiers. Simon Kitson informs this remarkable story with findings from his investigation—the first by any historian—of thousands of Vichy documents seized in turn by the Nazis and the Soviets and returned to France only in t...