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This book explores outcome modeling in cancer from a data-centric perspective to enable a better understanding of complex treatment response, to guide the design of advanced clinical trials, and to aid personalized patient care and improve their quality of life. It contains coverage of the relevant data sources available for model construction (panomics), ranging from clinical or preclinical resources to basic patient and treatment characteristics, medical imaging (radiomics), and molecular biological markers such as those involved in genomics, proteomics and metabolomics. It also includes discussions on the varying methodologies for predictive model building with analytical and data-driven ...
This contributed volume contains a collection of articles on state-of-the-art developments on the construction of theoretical integral techniques and their application to specific problems in science and engineering. The chapters in this book are based on talks given at the Fifteenth International Conference on Integral Methods in Science and Engineering, held July 16-20, 2018 at the University of Brighton, UK, and are written by internationally recognized researchers. The topics addressed are wide ranging, and include: Asymptotic analysis Boundary-domain integral equations Viscoplastic fluid flow Stationary waves Interior Neumann shape optimization Self-configuring neural networks This collection will be of interest to researchers in applied mathematics, physics, and mechanical and electrical engineering, as well as graduate students in these disciplines and other professionals for whom integration is an essential tool.