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This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical development of new molecularly targeted agents, the use of biomarkers as prognostic, predictive and surrogate endpoints, and the evaluation of tumor response and specific malignancies treated with targeted agents. The book also covers some of the newest developments in cancer therapy that are not adequately covered by any current available literature. Written by recognized experts in the field, Targeted Therapies for Solid Tumors: A Handbook for Moving Toward New Frontiers in Cancer Treatment provides a unique and valuable resource in the field of molecular oncology, both for those currently in training, and for those already in clinical or research practice.
Mariona y sus amigos de la agencia de detectives de Barcelona viajan a Roma. Su visita a El Coliseo coincide con el asesinato, en dicho monumento, del juez antimafia más famoso del país. Uno de los amigos es acusado de participar en dicha muerte y conducido a la cárcel más dura de dicha ciudad en la que permanecerá hasta que los otros dos descubren quién o quiénes es´tan detrás, no solo de sta crimen, sino también de toros asesinatos de diferentes servidores d ella ley italiana. La búsqueda de la verdad les hará conocer la vida alienante de la cárcel, la organización de la mafia por un integrante no siciliano, la belleza de la Ciudad Eterna, de la Costa Amalfitana o de Sicilia....
Illustrated with many color images, The Annotated Wuthering Heights provides those encountering the novel for the first time, as well as those returning to it, with a wide array of contexts in which to read Emily Brontë’s romantic masterpiece, which has been called “the most beautiful, most profoundly violent love story of all time.”
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Love & Passion Through The Ages is a riveting boxed-set collection that traverses the evolving landscapes of love and passion through the lenses of some of the most illustrious names in literature. Spanning centuries and encapsulating a variety of literary stylesfrom the refined elegance of the Regency period to the poignant realism of the late 19th centurythis anthology celebrates the timeless nature of human emotion and connection. It showcases the remarkable breadth of narrative techniques and thematic explorations, from the windswept moors of Brontë to the lavish courts of Dumas, illuminating the universality and diversity of romantic experience. The inclusion of seminal works by Mary W...
DigiCat presents to you the meticulously edited collection of the greatest historical romance novels: Uarda: A Romance of Ancient Egypt (Georg Ebers) The New Abelard: Love in the Times of Cathedrals (Robert Williams Buchanan) Hildebrand: The Days of Queen Elizabeth (Anonymous) Love-at-Arms (Rafael Sabatini) The Making Of A Saint (W. Somerset Maugham) The Cloister and the Hearth (Charles Reade) The Princess of Cleves (Madame de La Fayette) The Forest Lovers (Maurice Hewlett) Malcolm (George MacDonald) Scarlet Letter: Love in the Colonial Period (Nathaniel Hawthorne) The Wild Irish Girl (Lady Sydney Morgan) Sophia (Stanley John Weyman) Paul and Virginia (Bernardin de Saint-Pierre) Memoirs of E...
The 'Greatest Historical Romances of All Time' stands as a monumental anthology, capturing the riveting essence and breadth of historical romance through time. Within its pages, the collection showcases an exceptional variety of literary styles, from the sweeping, gothic emotional landscapes painted by the Brontë sisters to the intricate societal commentaries of Jane Austen and the intense passion of Leo Tolstoy's masterpieces. The anthology triumphs in bringing together standout pieces known for their deep exploration of love and society, adventure and self-discovery, all while embodying the historical and cultural nuances of their respective periods. It adeptly highlights the diversity an...
The Greatest Historical Novels of All Time is a meticulously curated anthology that traverses the rich and diverse landscape of historical fiction. Within its pages, readers will encounter a broad spectrum of literary styles, from the intricate social tapestries of Jane Austen and the Brontë sisters to the adventurous spirit of Alexandre Dumas and the poignant realism of Thomas Hardy. This collection not only showcases the multitudinous forms the genre can takeranging from romantic epics to biting social commentaries but also highlights its enduring significance in shaping our understanding of past cultures, societies, and individuals. The anthology succeeds in illustrating the evolution of...
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The 'Historical Romances Boxed Set' stands as a monumental collection, amalgamating an exquisite variety of literary styles that traverse the vast landscapes of classical and modern romances. This anthology encapsulates the thematic depths of love, societal norms, and the evolution of the romance genre over centuries. The diversity within embraces works that range from the passionate moors of England to the aristocratic salons of France, highlighting the remarkable versatility and depth of narratives from different periods. Notable for its inclusion of seminal pieces from several literary movements, the collection offers readers a comprehensive view of the historical evolution of romance lit...