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Chemical Linkers in Antibody-Drug Conjugates (ADCs)
Chemical Linkers in Antibody-Drug Conjugates aims to shine a detailed light on the various key attributes of chemical linkers in ADCs, for drug-to-antibody ratio, for stability, for release mechanism of payload, for pharmacokinetics, for stability determination, and for efficacy and safety.
Cycloadditions in Bioorthogonal Chemistry
The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
19th International Congress of Heterocyclic Chemistry
This book presents the abstracts of the 19th International Congress of Heterocyclic Chemistry (19th ICHC) held in Fort Collins, Colorado, 10-15th August 2003 and provides the reader with a topical comprehensive reference source covering the latest developments in the heterocycles area. Each lecture from the 19th ICHC is presented as a one page abstract containing a textual summary of the lecture, including references, figures and contact details of the author(s). Papers are divided into the following sections: heterocyclic natural products, heterocycles in organic synthesis, bioactive heterocycles, heterocyclic materials &related topics, heterocyclic pharmaceuticals. The book of abstracts provides a topical reference source covering the latest developments in the heterocyles area.
The Seventh Window
1997 was an important year for Sint Janskerk in Gouda, as the Museo del Prado in Madrid asked to borrow the cartoon of the King's Window by Dirck Crabeth for the exhibition 'Felipe II. Un prÃncipe del Renacimiento'. Inspired by this event, it was decided to compile an anthology about the church's seventh window. Based on the many-facetted topic an international group of scholars from various disciplines studied the stained-glass window in depth as a crucial presentation of Philip II's Netherlandish and English years. An important step in current research into an enthralling era in European history of the sixteenth century.
