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Synthetic Biology engineering complexity and refactoring cell capabilities
One of the key features of biological systems is complexity, where the behavior of high level structures is more than the sum of the direct interactions between single components. Synthetic Biologists aim to use rational design to build new systems that do not already exist in nature and that exhibit useful biological functions with different levels of complexity. One such case is metabolic engineering, where, with the advent of genetic and protein engineering, by supplying cells with chemically synthesized non-natural amino acids and sugars as new building blocks, it is now becoming feasible to introduce novel physical and chemical functions and properties into biological entities. The rule...
Synthetic Biology-Guided Metabolic Engineering
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Cancer Immunotherapy
This volume details multiple areas of new and emerging methods to develop the next generation of immunotherapy treatments. Chapters guide readers through analysis and characterisation of the interactions between tumour and immune cells, and cell engineering tools for cancer treatment, to provide a unique and compelling set of techniques instrumental to work with, and engineer, immune cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Immunotherapy: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Civil Structural Health Monitoring
This volume gathers the latest advances and innovations in the field of structural health monitoring, as presented at the 8th Civil Structural Health Monitoring Workshop (CSHM-8), held on March 31–April 2, 2021. It discusses emerging challenges in civil SHM and more broadly in the fields of smart materials and intelligent systems for civil engineering applications. The contributions cover a diverse range of topics, including applications of SHM to civil structures and infrastructures, innovative sensing solutions for SHM, data-driven damage detection techniques, nonlinear systems and analysis techniques, influence of environmental and operational conditions, aging structures and infrastructures in hazardous environments, and SHM in earthquake prone regions. Selected by means of a rigorous peer-review process, they will spur novel research directions and foster future multidisciplinary collaborations.
Selected Writings of an Eighteenth-Century Venetian Woman of Letters
Elisabetta Caminer Turra (1751-96) was one of the most prominent women in eighteenth-century Italy and a central figure in the international "Republic of Letters." A journalist and publisher, Caminer participated in important debates on capital punishment, freedom of the press, and the abuse of clerical power. She also helped spread Enlightenment ideas into Italy by promoting and publishing Voltaire's latest works and translating new European plays-plays she herself directed, to great applause, on Venetian stages. Bringing together Caminer's letters, poems, and journalistic writings, nearly all published for the first time here, Selected Writings offers readers an intellectual biography of this remarkable figure as well as a glimpse into her intimate correspondence with the most prominent thinkers of her day. But more important, Selected Writings provides insight into the passion that animated Caminer's fervent reflections on the complex and shifting condition of women in her society-the same passion that pushed her to succeed in the male-dominated literary professions.
Proceedings of the 10th International Operational Modal Analysis Conference
This volume gathers the latest advances and innovations in the field of operational modal analysis and structural health monitoring, as presented at the 10th International Operational Modal Analysis Conference (IOMAC), held in Naples, Italy on May 22-24, 2024. The contributions cover a diverse range of topics, including AI for data interpretation, automatic modal parameter estimation, Digital Twin, modal testing methods, instrumentation and case studies, model correlation and updating, modal-based SHM, modal mass estimation. Selected by means of a rigorous peer-review process, they will spur novel research directions and foster future multidisciplinary collaborations.
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