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Muscle Biopsy: A Practical Approach
2014 BMA Medical Book Awards Highly Commended in Pathology category! Muscle Biopsy: A Practical Approach gives you all of the unparalleled guidance necessary to effectively interpret and diagnose muscle biopsy specimens for the full range of diseases in both adults and children. Authored by Dr. Victor Dubowitz, internationally renowned figure in the field of muscle disease, this medical reference book takes an integrated approach to diagnosis and assessment of muscle biopsies that includes clinical, genetic, biochemical, and pathological features. It's the comprehensive, up-to-date coverage you need to evaluate muscle disorders with confidence "Overall, this is a well written and comprehensi...
Trends in Neuroimmunology
Immunology has developed quite impressively over the past decade and perhaps very few fields in medicine or biology have grown so explosively. Completely new fields have been elucidated in depth. We recall only the definition of the nature and function of RLA antigens at the molecular level. the chemical and functional identification of several cytokines. and the correlation to particular immunological functions of specific epitopes present on cellular mem branes. The extensive application of immunological techniques and concepts to the neurological sciences has led to the development of neuroimmunology. a disci pline in its infancy until few years ago. In these last years. neuroimmunology h...
Molecular Biology of RNA
RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth. This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme. This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself. This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology. Key pioneering experiments, which provided the underlying evidence for what we now know, ar...
Advances in Cardiomyopathies
This book is a comprehensive and up-to-date overview on the ethiology, pathophysiology, clinical and therapeutic aspects of cardiomyopathies, edited by distinguished clinical researchers, who designed and followed a prospective natural history study on cardiomyopathies. Particular emphasis is given to clinical relevance of basic science advances in the field, from genetics to immunology. Controversial therapeutic issues are discussed. An eminently practical section is devoted to beta-blockade, the most novel medical treatment for heart failure. Non medical treatment options from pacing to cardiomyoplasty, artificial assist devices and transplantation are reviewed.
Greenfield's Neuropathology, 2-Volume Set, Eighth Edition
Greenfield's Neuropathology, the worlds leading neuropathology reference, provides an authoritative, comprehensive account of the pathological findings in neurological disease, their biological basis and their clinical manifestations. This account is underpinned throughout by a clear description of the molecular and cellular processes and reactions that are relevant to the development, and normal and abnormal functioning of, the nervous system. While this scientific content is of paramount importance, however, care has been taken to ensure that the information is presented in a way that is accessible to readers working within a range of disciplines in the clinical neurosciences, and that als...
Greenfield's Neuropathology Eighth Edition 2-Volume Set
Greenfield's Neuropathology, the worlds leading neuropathology reference, provides an authoritative, comprehensive account of the pathological findings in neurological disease, their biological basis and their clinical manifestations. This account is underpinned throughout by a clear description of the molecular and cellular processes and reactions that are relevant to the development, and normal and abnormal functioning of, the nervous system. While this scientific content is of paramount importance, however, care has been taken to ensure that the information is presented in a way that is accessible to readers working within a range of disciplines in the clinical neurosciences, and that als...
Rennie & Roberton's Textbook of Neonatology E-Book
Thoroughly revised and updated, the New Edition of this definitive text explains how to care for neonates using the very latest methods. Of diagnosis and treatment.Rennie & Roberton's Textbook of Neonatology, 5th Edition represents the state-of-the-art on neonatal care, providing not only detailed pathophysiology and clinical chapters on every condition of the neonate but also comprehensive chapters on the psychosocial aspects of neonatology, such as handling perinatal death and ethical and legal aspects of neonatal care. Contributions from Fetal Medicine experts and Obstetricians provide valuable peripheral information essential to the practice of neonatology.Rennie & Roberton's Textbook of...
Muscular Dystrophy Therapeutics
This detailed book presents a comprehensive collection of state-of-the-art protocols on muscular dystrophy therapeutics, covering therapeutics using antisense oligonucleotides, gene replacement, genome editing, small molecules, stem cells, and antibodies. Written by leaders in the field, the volume explores techniques that are currently in use and are starting an exciting therapeutic revolution in muscular dystrophy. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Muscular Dystrophy Therapeutics: Methods and Protocols serves as an ideal resource to inspire readers and provide tips, strategies, and advice to develop new therapeutic technologies for this group of diseases.
Greenfield's Neuropathology - Two Volume Set
Greenfield's Neuropathology, the world’s leading neuropathology reference, provides a comprehensive account of the pathological findings in neurological disease, their biological basis, and their clinical manifestations. The book’s detailed advice on pathological assessment and interpretation is based on clear descriptions of molecular and cellular processes and reactions that are relevant to the development of the nervous system, as well as its normal and abnormal functioning. The information is presented in an accessible way to readers working within a range of disciplines in the clinical neurosciences, and neuropathological findings are placed within the context of a broader diagnosti...
