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Sun Protection in Man
"Sun Protection in Man" looks at the beneficial and harmful effects of solar radiation. The physiological consequences of sun exposure have been systematically studied starting at the end of the nineteenth century and we now have accumulated knowledge about how Caucasian and Asian skins reacts to solar radiation. The chemical effects of solar ultraviolet radiation have been analyzed with particular emphasis during the second half of the twentieth century. Research on micro-organisms has allowed us to understand the mechanisms of UV-induced mutagenesis and photosensitization. Studies with laboratory rodents have opened the path to the understanding of UV-induced immune-depression, carcinogene...
Environmental UV Photobiology
In response to the overwhelming concern for possible acute and long-term effects of ozone depletion on terrestrial and aquatic life, this volume presents a comprehensive collection of review articles from an internationally acknowledged group of experts.
Photomedicine
This Research Topic in Frontiers in Medicine offers a concise overview of the latest knowledge in the field of Photomedicine on therapeutic and preventive modalities, and UV pathogenesis of skin cancer. Photomedicine has revolutionized the treatment of inflammatory and neoplastic skin diseases over the last century since Niels Ryberg Finsen was awarded in 1903 the Nobel Prize “in recognition of his contribution to the treatment of diseases, especially lupus vulgaris, with concentrated light radiation, whereby he has opened a new avenue for medical science”. From then on, the field has moved on in leaps and bounds to expand phototreatment to many inflammatory as well as neoplastic skin diseases. With this Research Topic we aim to promote the field by giving the latest insights into Photomedicine’s therapeutic modalities and molecular mechanisms in treatment of diseases of the skin and beyond, as well as prevention from photodermatoses and carcinogenesis, as the dark sites of light. By engaging clinicians and scientists we intend to advance basic, clinical and translational research in the field of Photomedicine with its numerous facets.
Skin Cancer after Organ Transplantation
Organ transplantation has been performed for almost 40 years with steadily increasing success regarding long-time survival of the graft, as well as quality of life for the patient. However, graft tolerance only can be achieved via induction and maintenance of an impaired immunological surveillance. An increase of skin cancers as a consequence of the lowered cellular immunoresponse seems to parallel the overall increased long-time survival rate of organ transplant recipients. Against the background of chronic immunosuppression known risk factors like the amount of sun exposure prior and post transplantation, oncogenic viruses as well as the genetic background, and place of residence (latitude...
The Plague of Models
Sometimes, reading the news, it seems we are drowning in a sea of risks. Every day, dozens of news articles proclaim some activity, some exposure, some change in the environment exposes us to new and terrifying risks. And every day, governments in developed countries pop out regulations to ensure that we make those changes in behavior to address those supposed risks, whether we want to or not. You probably think such claims, and regulation of risk are backed up by something resembling actual real-world evidence of harm. You probably assume that governments, when regulating, are relying on hard data: physical observations of exposures to a potential harm, physical measurements of harms that r...
Protection of the Skin Against Ultraviolet Radiations
Are ultraviolet rays dangerous? This is the question addressed by the leading dermatological experts who compare their wide clinical experience in this book. It has now been established that ultraviolet rays provoke erythema and can cause considerable damage to blood vessels. But what is their precise impact on the occurrence of premature ageing and cancer of the skin, and other serious consequences? The specialists contributing to this work report on their observations and give objective and reasoned opinions on this question. Their explanations are rounded out by many colour illustrations and diagrams.
Singlet Oxygen, UV-A and Ozone
Recent advances in understanding the biological role of singlet oxygen in the pathways of cellular responses to ultraviolet-A radiation: its key position in photodynamical effects, and its generation by photochemical (dark) reactions, e.g. by cells of the immune system such as eosinophils and macrophages, are the focus of this volume. The new methods and techniques responsible for the rapid progress in this area are presented. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.
Unnatural Law
While governments assert that Canada is a world leader in sustainability, Unnatural Law provides extensive evidence to refute this claim. A comprehensive assessment of the strengths and weaknesses of Canadian environmental law, the book provides a balanced, critical examination of Canada's record, focusing on laws and policies intended to protect water, air, land, and biodiversity. Three decades of environmental laws have produced progress in a number of important areas, such as ozone depletion, protected areas, and some kinds of air and water pollution. However, Canada's overall record remains poor. In this vital and timely study, David Boyd explores the reasons why some laws and policies f...
