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Structure and Intrinsic Disorder in Enzymology offers a direct, yet comprehensive presentation of the fundamental concepts, characteristics and functions of intrinsically disordered enzymes, along with valuable notes and technical insights powering new research in this emerging field. Here, more than twenty international experts examine protein flexibility and cryo-enzymology, hierarchies of intrinsic disorder, methods for measurement of disorder in proteins, bioinformatics tools for predictions of structure, disorder and function, protein promiscuity, protein moonlighting, globular enzymes, intrinsic disorder and allosteric regulation, protein crowding, intrinsic disorder in post-translational, and much more. Chapters also review methods for study, as well as evolving technology to support new research across academic, industrial and pharmaceutical labs. - Unifies the roles of intrinsic disorder and structure in the functioning of enzymes and proteins - Examines a range of enzyme and protein characteristics, their relationship to intrinsic disorder, and methods for study - Features chapter contributions from international leaders in the field
An eminent pioneer of modern protein chemistry, Fruton (biochemistry emeritus, Yale U.) looks back on six decades in biochemical research and education to advance stimulating thoughts about science--how it is practical, how it is explained, and how its history is written. Annotation copyrighted by Book News, Inc., Portland, OR
A brief historical account of the background leading to the publication of the first four editions of the World Directory of Crystallographers was presented by G. Boom in his preface to the Fourth Edition, published late in 1971. That edition was produced by traditional typesetting methods from compilations of biographical data prepared by national Sub-Editors. The major effort required to produce a directory by manual methods provided the impetus to use computer techniques for the Fifth Edition. The account of the production of the first computer assisted Directory was described by S.C. Abrahams in the preface of the Fifth Edition. Computer composition, which required a machine readable dat...
Advances in Protein Chemistry
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