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The first book on Prognostics and Health Management of Electronics Recently, the field of prognostics for electronic products has received increased attention due to the potential to provide early warning of system failures, forecast maintenance as needed, and reduce life cycle costs. In response to the subject's growing interest among industry, government, and academic professionals, this book provides a road map to the current challenges and opportunities for research and development in Prognostics and Health Management (PHM). The book begins with a review of PHM and the techniques being developed to enable a prognostics approach for electronic products and systems. building on this founda...
Fungal natural products are among some of the earliest described sources of bioactive compounds. Basidiomycetes have been a prolific source of compounds, particularly as a source of antibiotics and antifungals. Despite advances in target-based and synthetic methods for drug discovery, natural products continue to be an important source of novel compounds. This book is a comprehensive guide to many important fungal species with a focus on their phytochemistry, potential sources of bioactive compounds, known chemistry and toxicology. This book is an ideal companion to researchers and postgraduates in phytochemistry and natural product pharmacology, and mycologists.
This volume contains the proceedings of the Second International Workshop on Hybrid Systems: Computation and Control (HSCC’99) to be held March 29- 31, 1999, in the village Berg en Dal near Nijmegen, The Netherlands. The rst workshop of this series was held in April 1998 at the University of California at Berkeley. The series follows meetings that were initiated by Anil Nerode at Cornell University. The proceedings of those meetings were published in the Springer-Verlag LNCS Series, Volumes 736, 999, 1066, 1201, and 1273. The p- ceedings of the rst workshop of the new series was published in LNCS 1386. The focus of the workshop is on modeling, control, synthesis, design, and ve- cation of ...
Appropriate selection of biochemical targets is one of the most important drivers of cost effectiveness in the discovery of new medicines. Despite the many advances in genetics, genomics and systems biology, ‘validation’ of a target is not achieved until therapeutic efficacy is demonstrated by a drug candidate. Volume 46 of this series reviews the medicinal chemistry aimed at six diverse targets from which important new medicines are emerging: * HIV integrase (discovery of the first-in-class inhibitor drug raltegravir)* 11-beta-Hydroxysteroid dehydrogenase (new approach to glucocorticoid regulation)* Nicotinic a7 choline receptor (agonists and positive allosteric modulators). * Bradykinin receptor (new approach to pain therapy)* Histone deacetylase (new drugs for cancer)* 5-HT2c receptor modulators (various CNS indications) *Presents the latest research in the field of drug discovery *Publishes on an annual basis to bring you the most innovative updates in medicinal chemistry *Available as an online resource via ScienceDirect
This book systematically presents a comprehensive framework and effective techniques for in-depth analysis, clear design procedure, and efficient implementation of diagnosis and prognosis algorithms for hybrid systems. It offers an overview of the fundamentals of diagnosis\prognosis and hybrid bond graph modeling. This book also describes hybrid bond graph-based quantitative fault detection, isolation and estimation. Moreover, it also presents strategies to track the system mode and predict the remaining useful life under multiple fault condition. A real world complex hybrid system—a vehicle steering control system—is studied using the developed fault diagnosis methods to show practical significance. Readers of this book will benefit from easy-to-understand fundamentals of bond graph models, concepts of health monitoring, fault diagnosis and failure prognosis, as well as hybrid systems. The reader will gain knowledge of fault detection and isolation in complex systems including those with hybrid nature, and will learn state-of-the-art developments in theory and technologies of fault diagnosis and failure prognosis for complex systems.
Discusses open systems, object orientation, software agents, domain-specific languages, component architectures, as well as the dramatic IT-enabled improvements in memory, communication, and processing resources that are now available for sophisticated control algorithms to exploit. Useful for practitioners and researchers in the fields of real-time systems, aerospace engineering, embedded systems, and artificial intelligence.
The topic of dynamic models tends to be splintered across various disciplines, making it difficult to uniformly study the subject. Moreover, the models have a variety of representations, from traditional mathematical notations to diagrammatic and immersive depictions. Collecting all of these expressions of dynamic models, the Handbook of Dynamic Sy
The field of Artificial Intelligence in Education includes research and researchers from many areas of technology and social science. This study aims to open opportunities for the cross-fertilization of information and ideas from researchers in the many fields that make up this interdisciplinary research area.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.