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Statistical Mechanics, Protein Structure, and Protein Substrate Interactions
A number of factors have come together in the last couple of decades to define the emerging interdisciplinary field of structural molecular biology. First, there has been the considerable growth in our ability to obtain atomic-resolution structural data for biological molecules in general, and proteins in particular. This is a result of advances in technique, both in x-ray crystallography, driven by the development of electronic detectors and of synchrotron radiation x-ray sources, and by the development ofNMR techniques which allow for inference of a three-dimensional structure of a protein in solution. Second, there has been the enormous development of techniques in DNA engineering which m...
The Delimitation of the Continental Shelf between Denmark, Germany and the Netherlands
Alex G. Oude Elferink's detailed analysis of the negotiations between Denmark, Germany and The Netherlands concerning the delimitation of their continental shelf in the North Sea makes use of the full range of government archives in these three States. He looks at the role of international law in policy formulation and negotiations, and explores the legal context, political considerations and, in particular, oil interests which fed into these processes. He also explains why the parties decided to submit their disputes to the International Court of Justice and looks at the preparation of their pleadings and litigation strategy before the Court. The analysis shows how Denmark and The Netherlands were able to avoid the full impact of the implications of the Court's judgment by sidestepping legal arguments and insisting instead on political considerations.
Synthesis of Marine Natural Products 2
Volumes five and six of Bioorganic Marine Chemistry differ from their predecessors in two respects - they deal exclusively with laboratory synthesis of marine natural products and they represent the effort of a single author and his associates. The rationale for these departures is readily perceived. For several decades organic synthesis has without doubt been the most spectacular branch of organic chemistry. While the late R.B. Woodward's dictum - organic compounds can undergo only four basic reactions: they can gain electrons; they can lose electrons; they can be transformed with acid or with base - is still true, the wealth and variety of available reagents which will accomplish chemical transformations has reached staggering proportions. Little wonder then, that synthetic methodology has achieved a high degree of predictability and total synthesis of natural products has been successfully directed toward ever more challenging targets. As for the second point, that of single authorship, multiple authorship would invariably have led to gaps and overlaps, thus making it difficult to assemble and assess recent research in a systematic and comprehens ive fashion.
Trace Analysis
Trace Analysis, Volume 4 presents critical discussions of selected topics in organic and inorganic analytical chemistry including instrumentation, techniques, and applications to the detection, identification, and quantitation of trace quantities of substances in a large variety of sample materials. The volume is directed towards topics in the trace analysis of biological materials and environmental samples. Chapters are devoted to discussions on developments and applications of ion-selective polymeric membrane electrodes for biological tissues and fluids; evaluation of X-ray emission spectroscopy for trace analysis; the use of solid adsorbents for pre-concentrating trace organic substances, mainly pollutants, from air; and comparison of neutron activation analysis and proton-induced X-ray emission spectroscopy for the determination of trace elements in rain and snow. Organic and inorganic chemists, medical technicians, and ecologists will find the book a good reference material.
Marine Organic Matter: Biomarkers, Isotopes and DNA
The oceans contain a great biodiversity of marine organisms. They include a rich variety of unusual genes and biochemistries and hence a diverse array of organic compounds ranging from colourful carotenoids and chlorophylls to lipids with structures ranging from the simple to the complex. This volume brings together ten chapters on the occurrence and identification of the lipid biomarkers and of pigments in marine waters. It describes how they can be used in conjunction with stable isotopes and molecular biology to ascertain the sources and fate of organic matter (both natural and pollutant) in the sea and underlying sediments. The authors are each experts in their field and the chapters provide both an overview of the state-of-the-art and knowledge gaps together with abundant detail to satisfy the needs of specialists and non-specialists alike.
Genetic Engineering
Volume 18 explores the latest advances in recombinant DNA molecule techniques and how they are revolutionizing basic research in biology. Chapters discuss obtaining good expression of genetically engineered pest-resistant genes introduced in crop plants, cloning DNAs containing palindromes, and identifying genes by 3' terminal exon trapping and much more.
Ordered Porous Solids
The developments in the area of ordered nanoporous solids have moved beyond the traditional catalytic and separation uses and given rise to a wide variety of new applications in different branches of chemistry, physics, material science, etc. The activity in this area is due to the outstanding properties of nanoporous materials that have attracted the attention of researchers from different communities. However, recent achievements in a specific field often remain out of the focus of collaborating communities. This work summarizes the latest developments and prospects in the area of ordered porous solids, including synthetic layered materials (clays), microporous zeolite-type materials, orde...
Reviews of Environmental Contamination and Toxicology
Reviews of Environmental Contamination and Toxicology contains timely review articles concerned with all aspects of chemical contaminants (including pesticides) in the total environment, including toxicological considerations and consequences. It attempts to provide concise, critical reviews of advances, philosophy, and significant areas of accomplished or needed endeavor in the total field of residues of these and other foreign chemicals in any segment of the environment, as well as toxicological implications.
The PCR Revolution
Examines the latest innovations and the overall impact of PCR on areas of molecular research.
Methods in Enzymology
The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.
