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The application of hemodiafiltration has been restricted until recently, when a broader clinical application has been made possible due to evidence from large studies and clinical investigations. This book provides an updated review of the evolution, advances and recent results achieved by hemodiafiltration in the clinical arena. The first part is devoted to historical notes and an outline of the evolution of different forms of hemodiafiltration, made possible by technological developments in the fields of membranes, machines and fluids. The next section describes the theoretical rationale for hemodiafiltration, providing a detailed analysis of the involved mass separation processes, the hyd...
Since high-permeability membranes were first introduced, their performance has constantly improved. The publication at hand focuses on a new polymer, polyethersulfone, which was designed to provide better hydraulic permeability as well as high diffusive performance, thus allowing for fine tuning for different clinical applications. In the first part of the book, physico-chemical characteristics and ultrastructural features of the polyethersulfone membrane with regard to different clinical uses ranging from low to high permeability membranes are dealt with. The second part is devoted to clinical applications of the polyethersulfone membrane in ESRD. Its high biocompatibility, combined with th...
Over the last decade, the availability of new devices and membranes has led to the development of modern hemodialysis techniques in which clinical tolerance and efficiency have significantly improved patient morbidity and mortality. Nevertheless, there are still limitations imposed by hemodialysis, manifested by the long-term complications occurring in patients treated for several years.Since most of these complications seem to be related to the chronic inflammation of ESRD patients and the progressive accumulation of middle-large molecules such as beta-2-microglobulin, GIP, leptin and others, a novel approach is needed, capable of adequately removing these substances from the body of the pa...
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Since the inaugural publication of Pediatric Dialysis in 2004, a wide range of advances have taken place in dialysis-related care, leading to a wealth of new knowledge in the field. Pediatric Dialysis, Second Edition brings this knowledge together to provide the most comprehensive source of state-of-the-art information on the dialysis of infants, children and adolescents. With new chapters, updated chapters and references, and contemporary, unique perspectives from authors who are leaders in the global pediatric nephrology community, Pediatric Dialysis, Second Edition is, once again, an authoritative reference that will facilitate best practices in both acute and chronic dialysis. Experienced clinicians and trainees alike will find Pediatric Dialysis, Second Edition not only another valuable contribution to the literature but an indispensable guide to managing their pediatric patients on dialysis.
While continuous ambulatory peritoneal dialysis (CAPD) has been the standard peritoneal procedure since the seventies, different schedules of automated peritoneal dialysis (APD) have emerged during the eighties. Today, APD is considered a valuable tool in the management of ESRD patients, together with CAPD and hemodialysis. However, despite its frequent use, APD has not yet been well assessed, and most pathophysiological and clinical studies on PD refer to CAPD. In this book, major experts in the field therefore discuss and evaluate the insights gained on APD up to now, presenting a comprehensive review of all experimental, technical and clinical aspects related to the various treatments gro...
Limited Responsibilities explores the interaction between the criminal justice system and the wider concerns of political and social institutions, including the welfare state, social work and forensic psychiatry. Using the key concept of `responsibility', Tamar Pitch critiques the classical theories of Anglo-American and Italian criminologies, examining the allocation of responsibilities to individuals and society. Looking at the shifting political relationship between criminal justice and the welfare system, Pitch considers the problems which arise in our understandings of responsibility, particularly in relation to the young and the mentally disabled. She also documents the centrality of responsiblity as an issue in women's struggles for legislation on sexual violence, as a paradigm of the politicisation of notions of crime, victimization and criminal responsibility. Limited Responsiblities will be of interest to lecturers, students and professionals in criminology, social policy and women's studies.
Completely revised edition of a global resource first published in 1978 and previously revised in 1989. Sixty-three contributions are arranged in sections on the pathophysiology of the uremic syndrome--principles and biophysics of dialysis; technology of dialysis and associated methods; quantification and prescription; complications; pharmacological considerations; special clinical situations; organ system and metabolic complications; and organization and results of chronic dialysis. The aim is to give understanding of the complexities of modern dialysis apparatus so that practitioners can make the best use of the technology--and so that fledgling nephrologists can avoid the temptation to by-pass the theory and the nuances. Annotation copyright by Book News, Inc., Portland, OR