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Biochemistry and Cell Biology of Ageing: Part II Clinical Science
This volume of the subcellular Biochemistry series will attempt to bridge the gap between the subcellular events that are related to aging as they were described in the first volume of this set of two books and the reality of aging as this is seen in clinical practice. All chapters will start from the biochemistry or cell biology, where the data is available and work up towards the understanding that we have of aging in the various areas that are related to the subject. Key focus points for this volume are nutrition, external factors and genetics on aging. There will also be chapters that will focus on various organs or tissues in which aging has been well studied, like the eyes, the muscles, the immune system and the bones. The aim of the book project and the book project that is published in concert with this volume is to bring the subcellular and clinical areas into closer contact.
Handbook of Models for Human Aging
The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. - Utilizes a multidisciplinary approach - Shows tricks and approaches not available in primary publications - First volume of its kind to combine both methods of study for human aging and animal models - Over 200 illustrations
Immunology of Aging
The rapidity of scientific progress over the last few years guarantees the utility of this new collection of state-of-the-art reviews on the immunology of aging, which is the result of extensive collaboration of more than sixty of the greatest thinkers and scholars in the field, in cooperation with a number of junior colleagues. The book summarizes current knowledge on the cellular and molecular aspects of the aging immune system and their clinical relevance, providing insights into the effects of the aging process on susceptibilities to those diseases most common among elders. The retrieval strategies used to slow down the decline in the immune system in the elderly are another subject detailed extensively. By providing a broad overview of immunosenescence and its consequences, as well as their potential modulation, this book will fill a gap in a timely manner. It will be of value to all immunologists, whether novice or experienced, as well as geriatricians and epidemiologists.
Aging Methods and Protocols
Aging is an almost universal process within biological systems, one which leads to a decline in functional capacity, disease onset, and eventually death. There has been much interest in recent years to elucidate the molecular mec- nisms that underlie the aging process. Many theories have been proposed since the last century that aim to explain the causes of aging. There is no one theory that completely satisfies the phenotype of aging, but genetics and environm- tal factors play an important role in the etiology of age-related pathologies and the aging process. However, there is still much to be learned about the aging process which has been termed one of the last great frontiers in biology....
Anti-aging Drugs
Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medicatio...
Annual Reports in Medicinal Chemistry
Annual Reports in Medicinal Chemistry
Nanocatalysis
Nanocatalysis is one of the most exciting subfields to have emerged from nanoscience. Its central aim is the control of chemical reactions by changing the size, dimensionality, chemical composition and morphology of the reaction center and by changing the kinetics using nanopatterning of the reaction centers. This approach opens up new avenues for atom-by-atom design of nanocatalysts with distinct and tunable chemical activity, specificity, and selectivity. This book is intended to give a pedagogical and methodological overview of this exciting and growing field and to highlight specific examples of current research. In this way, it serves both as an instructive introduction for graduate students who plan to enter the field and as a reference work for scientists already active in this and related areas.
Translational Autoimmunity, Volume 6
Translational Autoimmunity: Advances in Autoimmune Rheumatic Diseases, Volume Six addresses autoimmune diseases classified under the category of rheumatic diseases. Rheumatic diseases are heterogeneous groups of disorders in which inflammation affects not only joints, but also tendons, ligaments and bones. This updated release focuses on immunopathogenesis and clinical and laboratory details of rheumatic diseases, including rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, osteoarthritis and Sjogren's syndrome, and will be of interest to researchers, students and clinicians interested in autoimmune diseases, especially rheumatic diseases. From an introduction to rheuma...
