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Photon Migration in Tissues
This book is formulated from a number of presentations made at a one-day workshop on the subject of Photon Migration in Tissues. The meeting was held in Philadelphia at the University of Pennsylvania, April, 1988. The workshop was an impromptu effort to bring together scientists to discuss photon migration in animal tissues and appropriate models. The rapid emergence of the ideas of Townes and Schalow in their invention of the then called maser, now laser opened up completely unexpected possibilities for biomedical research. Timing of rapid biochemical reaction, identification of unstable intermediates, spectroscopy of short lived fluorescent states were all goals to be expected and achieved. At the same time continuous light spectroscopy of tissue slices and of the myocardium, and eventually of the brain have the to the the neonate emerged over years. Shifting red end of spectrum, Butler and Norris clearly showed how transparent plant materials and the human hand could be illuminated in this region and Jobsis applied their idea to the neonate brain using a multiwavelength technique.
Lasers in Polymer Science and Technolgy
The purpose of this 4-volume set is to examine some of the applications of lasers in polymer science and technology. Now available for the first time, up-to-date information on this fascinating subject is compiled and presented in compact form. This set focuses on current research and developments in the application of lasers in polymer and biopolymer chemistry. It includes experimental and theoretical details, apparatus, techniques, and applications. This set is a useful source for researchers, students, polymer chemists, and physicists involved in this astonishing field of high technology.
Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields
This book presents the latest technological advances in Raman spectroscopy that are presently redrawing the landscape of many fields of biomedical and pharmaceutical R&D. Numerous examples are given to illustrate the application of the new methods.
Optical Microendoscopy for Imaging Cells Lying Deep Within Live Tissue
Optical microendoscopy is an emerging modality for imaging in live subjects. Using gradient refractive index (GRIN) microlenses, microendoscopy enables subcellular-resolution imaging in deep tissues that are inaccessible by traditional imaging techniques. We present a platform of methods and technologies that build upon GRIN microendoscopy: 1) miniaturized microscopes for imaging in awake, behaving animals, 2) methods for imaging contractile dynamics in the muscles of animal and human subjects, 3) chronic brain preparations that allow for longitudinal examinations of subcellular neuronal features and disease progression, and 4) novel microendoscope probes whose imaging capabilities approach that of standard water-immersion microscope objectives. When combined with the broad sets of available fluorescent reporters, and minimally invasive surgical preparations, the work described in this dissertation enables sophisticated experimental designs for probing how cellular char- acteristics may underlie or explain behavior, in models of both healthy and diseased states.
Laser Imaging and Manipulation in Cell Biology
Here, the editor has gathered a team of international experts to present the latest advances in the field of laser imaging and manipulation techniques. The result is broad coverage of the interactions with biological samples to perform novel optical manipulation operations, both on the cellular and tissue levels. Of interest to physicists working and researching laser tissue mechanisms, cell biologists investigating new imaging and manipulation operation on the cellular level, medical doctors working with new laser therapies and diagnostic tools, as well as engineers developing new technologies in the field of optics and lasers.
