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Antimicrobial Pharmacodynamics in Theory and Clinical Practice
  • Language: en
  • Pages: 427

Antimicrobial Pharmacodynamics in Theory and Clinical Practice

  • Type: Book
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  • Published: 2001-09-25
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  • Publisher: CRC Press

This up-to-the-minute reference explores the pharmacodynamics of antimicrobials as well as the absorption, distribution, metabolism, and elimination of the major classes of antimicrobials-covering new agents such as ketolide antibiotics and highlighting the pharmacodynamic relationship between drug concentration and antimicrobial activity, as well as the relationship of pharmacodynamics to bacterial resistance. Contains specific examples and practical applications for the design of effective dosing regimens! Written by recognized experts in the field, Antimicrobial Pharmacodynamics in Theory and Clinical Practice describes the pharmacodynamic properties of all major classes of antibiotics pa...

Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics
  • Language: en
  • Pages: 467

Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical rese...

Antimicrobial Resistance
  • Language: en
  • Pages: 520

Antimicrobial Resistance

  • Type: Book
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  • Published: 2007-12-22
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  • Publisher: CRC Press

This publication provides a state-of-the-art overview of key issues related to antimicrobial resistance, including a focus on key pathogens causing common healthcare-associated and community-acquired infections. The epidemiology and therapeutic considerations of these antimicrobial resistant organisms are discussed, as well as the clinical and heal

Clinical Trial Simulations
  • Language: en
  • Pages: 540

Clinical Trial Simulations

This edition includes both updates and new uses and issues concerning CTS, along with case studies of how clinical trial simulations are being applied in various therapeutic and application areas. Importantly, the book expands on the utility of CTS for informing decisions during drug development and regulatory review. Each chapter author was selected on the basis of demonstrated expertise in state-of-the-art application of CTS. The target audience for this volume includes researchers and scientists who wish to consider use of simulations in the design, analysis, or regulatory review and guidance of clinical trials. This book does not embrace all aspects of trial design, nor is it intended as a complete recipe for using computers to design trials. Rather, it is an information source that enables the reader to gain understanding of essential background and knowledge for practical applications of simulation for clinical trial design and analysis. It is assumed that the reader has a working understanding of pharmacokinetics and pharmacodynamics, modeling, pharmacometric analyses, and/or the drug development and regulatory processes.

Antimicrobial Drug Resistance
  • Language: en
  • Pages: 692

Antimicrobial Drug Resistance

This ? rst edition of Antimicrobial Drug Resistance grew out of a desire by the editors and authors to have a comprehensive resource of information on antimicrobial drug resistance that encompassed the current information available for bacteria, fungi, protozoa and viruses. We believe that this information will be of value to clinicians, epidemiologists, microbiologists, virologists, parasitologists, public health authorities, medical students and fellows in training. We have endeavored to provide this information in a style which would be accessible to the broad community of persons who are concerned with the impact of drug resistance in our cl- ics and across the broader global communities...

Clinical Infectious Diseases
  • Language: en
  • Pages: 1058

Clinical Infectious Diseases

Noted in Annals of Pharmacotherapy

Clinical Handbook of Pediatric Infectious Disease
  • Language: en
  • Pages: 338

Clinical Handbook of Pediatric Infectious Disease

  • Type: Book
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  • Published: 2007-08-22
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  • Publisher: CRC Press

In the care of pediatric patients, infectious diseases comprise over 50% of the clinical diagnoses. For this reason, it is essential to have a basic understanding of infectious processes and to keep abreast of new developments in the field. This reference stands as a convenient and time-saving reference for clinicians on the diagnosis, treatment, a

Infectious Diseases in Critical Care Medicine
  • Language: en
  • Pages: 586

Infectious Diseases in Critical Care Medicine

  • Type: Book
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  • Published: 2009-10-28
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  • Publisher: CRC Press

A clinically focused overview of infectious disease and critical care medicine.The Third Edition of Infectious Disease in Critical Care Medicine presents clear diagnostic methods, strategies, and knowledge on antimicrobials crucial to avoiding complications and ensuring patient recovery in the CCU. Comprehensive yet succinct, this source discusses

Lennette's Laboratory Diagnosis of Viral Infections
  • Language: en
  • Pages: 512

Lennette's Laboratory Diagnosis of Viral Infections

  • Type: Book
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  • Published: 2016-04-19
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  • Publisher: CRC Press

Written from the perspective of the diagnostician, this bestselling book is the definitive text on the laboratory diagnosis of human viral diseases. It contains a wealth of illustrations, tables, and algorithms to enhance your understanding of this ever-evolving field. The book is a ready reference for virologists, microbiologists, epidemiologists, laboratorians, and infections disease specialists, and students.

Diagnosis of Fungal Infections
  • Language: en
  • Pages: 425

Diagnosis of Fungal Infections

  • Type: Book
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  • Published: 2007-08-29
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  • Publisher: CRC Press

Analyzing a key cause of infectious morbidity in immunosuppressed and immunocompromised patients, this source spans the most recent strategies to improve and expedite the diagnosis, identification, and treatment of fungal infections. With authoritative contributions from experienced clinicians in the field, this reference tracks developments in ima