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Recent Progress in Hormone Research, Volume 48 provides information pertinent to endocrine research dealing with all aspects of biological organization. This book covers a variety of topics, including differentiation of the embryo, development and growth at puberty, maintenance of adult well-being, and aging. Organized into 29 chapters, this volume begins with an overview of the role of oncogenes in fetal development. This text then compares the molecular descriptions of the genes for growth hormone and prolactin receptors to receptors for s variety of other hormones, peptide, and growth factors. Other chapters consider the three-dimensional structure of the growth hormone receptor. This book discusses as well the conventional and nonconventional uses of human growth hormone, with emphasis on the wide availability of protein that is possible only through molecular biology. The final chapter deals with the effect of hormones on primate behavior. This book is a valuable resource for geneticists and biologists.
Since our previous symposium in 1995, the pace of research in hormones and cancer has accelerated. Progress in our understanding of hormonal carcinogenic processes has been a direct result of the advances made in cell biology, endocrinology, and carcinogenesis at the molecular level. The newer fields of molecular genetics and cytogenetics already have and are expected to continue to playa major role in furthering our understanding of the cellular and molecular events in hormonal carcinogenesis. It has become increasingly clear that the risk of naturally occurring sex hormones in carcinogenic processes, both in human and in animal models, requires only minute quantities of hormones, at both t...