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Originada a partir do “Seminário de Direitos Humanos e Novos Direitos na Contemporaneidade”, promovido pelo Grupo de Estudos “PACTO – Paz, Cultura e Tolerância”, realizado nas dependências da Faculdade de Filosofia e Ciências da Universidade Estadual Paulista (Unesp), campus de Marília, na cidade de Marília/SP, em 04 de maio de 2018, a presente obra tem por objetivo publicar trabalhos de natureza acadêmico-científica sobre a temática fundamental dos direitos humanos e de direitos emergentes nesta época contemporânea. Agrega entre os autores que assinam os capítulos, pesquisadores de diferentes instituições de ensino superior, de vários níveis acadêmicos e de variad...
A obra Direito, Tecnologia e Inovação reúne pesquisadores, discentes e docentes de instituições de Ensino Superior brasileiras que dedicam seus esforços no enfrentamento das nuances do Direito Digital e que foram ou estão vinculados ao programa de Mestrado em Direito do Univem e ao Nepi.
Immunologists, perhaps understandably, most often concentrate on the human immune system, an anthropocentric focus that has resulted in a dearth of information about the immune function of all other species within the animal kingdom. However, knowledge of animal immune function could help not only to better understand human immunology, but perhaps more importantly, it could help to treat and avoid the blights that affect animals, which consequently affect humans. Take for example the mass death of honeybees in recent years – their demise, resulting in much less pollination, poses a serious threat to numerous crops, and thus the food supply. There is a similar disappearance of frogs interna...
Ensuring quality and affordability in the water services is a fundamental requirement for the social, economic and environmental development of modern societies. Achieving this goal requires dealing with a large diversity of challenges, such as efficiency, investment, governance, procurement and sustainability, while ensuring the alignment of the stakeholder's objectives, often with conflicting expectations. Public-private Partnerships (PPPs) have emerged as a desirable model for Governments to develop and improve water services, particularly due to the shortage of public financing. Although PPPs have proven to be able to deliver value for money in public services provision, the empirical ev...
Fifty years after the foundation of the OAU and the consolidation of most African states and institutions, the international panorama and Africa’s position in it have changed considerably. The world's geopolitical and economic configuration has evolved, with new actors appearing in a new period of globalization. In tone with ECAS 2013, this volume proposes that the experiences appearing in Africa question dominant paradigms in terms of political practice and academic reflection and thus offer a clear challenge to the academic community. The volume offers clues to answer questions such as: What is the impact of the current processes of globalization for African countries and African citizens? How should African Studies be engaged to gauge African dynamics, both at a local and global level? What interdisciplinary means and tools should be brought in to produce an epistemologically relevant view (or narrative) of the issues under analysis?
Epigenetic mechanisms (DNA modifications, histone alterations and non-coding RNAs) are crucial for transcriptional regulation and alterations of the “physiological epigenome” are increasingly associated with human diseases. During the last decade the emerging field of neuroepigenomics have started to impact tremendously in areas such learning and memory, addiction or neurodegeneration. This expert volume covers the role of epigenetic molecular mechanism in regulation of central nervous system’s function, one of the most exciting areas of contemporary molecular neuroscience. The book describes the current knowledge on the epigenetic basis of human disease covering the complete lifespan:...
Molecular chaperones or heat-shock proteins (HSPs) play essential roles in safeguarding structural stability and preventing misfolding and aggregation of proteins, and maintaining the proteome functionality in the cell. For over two decades until the present time, new functions have been discovered and several molecular mechanisms have been elucidated for many chaperones, while the field is being continuously challenged by new open questions. Probably as a consequence of the increasing research on the molecular bases of neurodegenerative diseases, and the realisation that many such disorders are linked to protein misfolding processes, unleashing the roles and mechanisms of chaperones in the context of neurodegeneration has become a prime scientific goal. This e-book contains a diversity of reviews, perspective and original research articles highlighting the importance and potential of this emerging subject.
We test the effect of foreign direct investment (FDI) on economic growth in a cross-country regression framework, utilizing data on FDI flows from industrial countries to 69 developing countries over the last two decades. Our results suggest that FDI is an important vehicle for the transfer of technology, contributing relatively more to growth than domestic investment. However, the higher productivity of FDI holds only when the host country has a minimum threshold stock of human capital. In addition, FDI has the effect of increasing total investment in the economy more than one for one, which suggests the predominance of complementarity effects with domestic firms.
Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies. This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment. - Provides a comprehensive overview of how key proteins in neurodegenerative disorders can be used as targets to modify disease progress - Summarizes how patients are treated today, providing a glance at future disease management - Includes intelligible and informative information that is perfect for non-specialists, medical practitioners, and scientists - Written and peer reviewed by outstanding scientists in their respective fields