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Current Catalog
First multi-year cumulation covers six years: 1965-70.
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Fibronectins
Fibronectins comprise a class of high molecular weight glycoproteins present both in extracellular matrices and in soluble form in body fluids. Although they have been studied for about forty years, their real significance emerged only during the past decade. Intensive research has focused on their role in platelet function, cell migration, the cytoskeleton, reticuloendothelial function, and on alterations in fibronectin distribution during development and disease. Fibronectins have emerged as glycoproteins with a very interesting set of properties generally involving adhesion of cells to cells or to extracellular material. In more recent years, the complete sequences of several fibronectin molecules and their genes were determined, the relation between structure and function was understood and much has been learned about cell surface receptors for fibronectins and other adhesive ligands. Having been at the forefront of all these exciting developments, the author has synthesized the entire field and with all the latest information at hand for the first time given it a clear perspective.
Iron Metabolism
Iron plays a crucial role in many biochemical processes. In recent years intensive research has led to a better understanding of the function of iron in cellular metabolism. In more than twenty articles internationally renowned experts give a thorough account of the recent developments of this fascinating field. The book focuses on the central questions, e.g. transport, storage, and utilization of iron in cells, the three-dimensional structure of iron-containing proteins, the physiological function of heme and iron sulfur-containing proteins, and the regulatory mechanisms in heme biosynthesis and redox regulation of signal transduction. The interdisciplinary character of the book is designed to explore the many facets of the new findings and to provide a comprehensive overview of recent advances for biochemists, bioinorganic chemists, molecular biologists, microbiologists and immunologists. The reviews are supplemented with valuable background information, results and numerous references. This book emphasizes the relationships between the different disciplines concerned with iron metabolism and opens new perspectives for future research!
Reconstructing Response to Student Writing
In Reconstructing Response to Student Writing Dan Melzer makes the argument that writing instructors should shift the construct so that peer response and student self-assessment are more central than teacher response. Presenting the results of a national study of teacher and peer response and student self-assessment at institutions of higher education across the United States, Melzer analyzes teacher and peer response to over 1,000 pieces of student writing as well as 128 student portfolio reflection essays. He draws on his analysis and on a comprehensive review of the literature on response to introduce a constructivist heuristic for response aimed at both composition instructors and instru...
Chromatin
Contemporary views on the structure and function of chromatin are presented and the history of the development of these ideas as well as the nature of the nucleic acid and protein components of chromatin are reviewed. The structure of chromatin is studied at several levels, and its modes of transcription and replication are analyzed. Chromatin provides researchers with a critical evaluation of current knowledge. It combines much information that has never before been assembled, and evaluates and interrelates it in a critical way. This has not been done before so that readers are not only provided with an overview, but with extensive references to the literature (there are about 2000 references in all).
Linear Aggregation Theory in Cell Biology
During the past few decades we have witnessed an era of remarkable growth in the field of molecular biology. In 1950 very little was known ofthe chemical constitution of biological systems, the manner in which information was transmitted from one organism to another, or the extent to which the chemical basis oflife is unified. The picture today is dramatically different. We have an almost bewildering variety of information detailing many different aspects of life at the molecular level. These great advances have brought with them some breathtaking insights into the molecular mechanisms used by nature for replicating, distributing, and modifying biological information. We have learned a great...
Biochemistry and Physiology of Protozoa
Biochemistry and Physiology of Protozoa, Second Edition, Volume 1 is organized into 13 chapters, beginning with a discussion on fine structure and phytogeny of phytoflagellates. This book discusses the structural features of protozoan cytochromes. Subsequent chapters explain sterol and carotenoid distributions in various groups, phycobiliproteins in cryptomonads, halotolerance in Dunaliella, physiology of coccolithophorids, the ameboflagellates, and bioluminescence of phytoflagellates. This edition also describes the most severe and best known of the toxins, saxitoxin, produced by species of Gonyaulax. Lastly, the physiological ecology of red tide flagellates is explained.
Cytochromes c
Cytochromes c are haemoproteins which carry out electron transfer in a wide variety of biological systems, necessitating different kinds of cytochrome c to fulfill different biological roles. The evolutionary relationship between cytochromes c and their host organisms are described, as well as their structural, spectroscopic and redox properties, including both electron-transfer rates and redox potentials. The treatment is aimed at the non-specialist so that both the techniques described and their application to cytochromes c can be understood. All classes of cytochrome c are dealt with to provide a comprehensive account of the field. No other text provides such a broad survey. Similar to the earlier volume "Cytochromes c: Biological Aspects" which deals with the classification, biosynthesis and biological role of cytochromes c, the present book is aimed at research workers and advanced students.
