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Cloud computing has created a shift from the use of physical hardware and locally managed software-enabled platforms to that of virtualized cloud-hosted services. Cloud assembles large networks of virtual services, including hardware (CPU, storage, and network) and software resources (databases, message queuing systems, monitoring systems, and load-balancers). As Cloud continues to revolutionize applications in academia, industry, government, and many other fields, the transition to this efficient and flexible platform presents serious challenges at both theoretical and practical levels—ones that will often require new approaches and practices in all areas. Comprehensive and timely, Cloud ...
This textbook presents a special solution to underdetermined linear systems where the number of nonzero entries in the solution is very small compared to the total number of entries. This is called a sparse solution. Since underdetermined linear systems can be very different, the authors explain how to compute a sparse solution using many approaches. Sparse Solutions of Underdetermined Linear Systems and Their Applications contains 64 algorithms for finding sparse solutions of underdetermined linear systems and their applications for matrix completion, graph clustering, and phase retrieval and provides a detailed explanation of these algorithms including derivations and convergence analysis. Exercises for each chapter help readers understand the material. This textbook is appropriate for graduate students in math and applied math, computer science, statistics, data science, and engineering. Advisors and postdoctoral scholars will also find the book interesting and useful.
Prostate cancer (PCa) is among the most diagnosed cancers in men worldwide as well as one of the most common causes of cancer-related deaths. Despite the advances in treatment, the disease remains associated with poor survival and resistance to cytotoxic and targeted therapies. Therapy Resistance in Prostate Cancer: Mechanisms and Insights highlights the main mechanisms that are responsible for therapy resistance in PCa allowing researchers and clinicians to have a synopsis of current options and new therapies that can be proposed to overcome this resistance. Understanding the mechanisms responsible for chemotherapy resistance helps researchers all over the world to delve deeper into the pat...
Sparse grids are a popular tool for the numerical treatment of high-dimensional problems. Where classical numerical discretization schemes fail in more than three or four dimensions, sparse grids, in their different flavors, are frequently the method of choice. This volume of LNCSE presents selected papers from the proceedings of the fifth workshop on sparse grids and applications, and demonstrates once again the importance of this numerical discretization scheme. The articles present recent advances in the numerical analysis of sparse grids in connection with a range of applications including uncertainty quantification, plasma physics simulations, and computational chemistry, to name but a few.
Computers and automation have revolutionized the lives of most people in the last two decades, and terminology such as algorithms, big data and artificial intelligence have become part of our everyday discourse. This book presents the proceedings of CAIBDA 2023, the 3rd International Conference on Artificial Intelligence, Big Data and Algorithms, held from 16 - 18 June 2023 as a hybrid conference in Zhengzhou, China. The conference provided a platform for some 200 participants to discuss the theoretical and computational aspects of research in artificial intelligence, big data and algorithms, reviewing the present status and future perspectives of the field. A total of 362 submissions were r...
This book constitutes the refereed proceedings of the 22nd Smoky Mountains Computational Sciences and Engineering Conference on Accelerating Science and Engineering Discoveries Through Integrated Research Infrastructure for Experiment, Big Data, Modeling and Simulation, SMC 2022, held virtually, during August 23–25, 2022. The 24 full papers included in this book were carefully reviewed and selected from 74 submissions. They were organized in topical sections as follows: foundational methods enabling science in an integrated ecosystem; science and engineering applications requiring and motivating an integrated ecosystem; systems and software advances enabling an integrated science and engineering ecosystem; deploying advanced technologies for an integrated science and engineering ecosystem; and scientific data challenges.
This book presents the role of nanoparticles in cancer therapy, emphasizing their innovative applications across treatment, diagnosis and the development of therapeutic strategies. The first section of the book describes the applications of nanoparticles in cancer vaccines and gene therapy. It features discussions on polymeric nanoparticles as nanovaccine carriers, membrane-based nano-vaccines for immunotherapy and gene therapy techniques employing nanoparticles. The second section presents advanced nanomedicine approaches, specifying the role of chemodynamic nanoparticles in cancer theranostics, the application of low-dimensional nanomaterials and emerging strategies against drug resistance...