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HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.
This volume includes extended and revised versions of a set of selected papers from the International Conference on Electric and Electronics (EEIC 2011) , held on June 20-22 , 2011, which is jointly organized by Nanchang University, Springer, and IEEE IAS Nanchang Chapter. The objective of EEIC 2011 Volume 2 is to provide a major interdisciplinary forum for the presentation of new approaches from Electrical engineering and controls, to foster integration of the latest developments in scientific research. 133 related topic papers were selected into this volume. All the papers were reviewed by 2 program committee members and selected by the volume editor Prof. Min Zhu. We hope every participant can have a good opportunity to exchange their research ideas and results and to discuss the state of the art in the areas of the Electrical engineering and controls.
Many fundamental aspects of the methods used in mass spectrometry are here presented by outstanding scientists, with reference to very recent developments. The principles and applications of electrospray, ion spray and MALDI ionization technique are presented, together with optimised GC/MS interfacing systems and tools for quantitative analysis. A comprehensive treatment of modern instrumentation for mass analysis and detection is also included. The major part of the book deals with bioanalytical applications to peptides, proteins, oligonucleotides, polysaccharides, lipids and plant metabolites. Several papers are devoted to the evaluation of adduct formation between DNA and carcinogens. Env...
Providing a detailed understanding of why heat and electricity energy storage technologies have developed so rapidly, Future Grid-Scale Energy Storage Solutions: Mechanical and Chemical Technologies and Principles presents the required fundamentals for techno-economic and environmental analysis of various grid-scale energy storage technologies. Through a consistent framework, each chapter outlines state-of-the-art advances, benefits and challenges, energy and exergy analyses models of these technologies, as well as an elaboration on their performance under dynamic and off-design operating conditions. Chapters include a case study analysis section, giving a detailed understanding of the syste...