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Current Catalog
First multi-year cumulation covers six years: 1965-70.
Metastasis
The Metastasis Group of the European Organization for Research on Treatment of Cancer (EORTC) held an International Meeting at the Royal Institution in London on April 2lst-23rd, 1980. The subject was "Clinical and Experimental Aspects of Metastasis" and these Proceedings are the record of that Meeting. Almost all of those who presented a paper or a poster have written up their contributions as chapters of the Proceedings and we have made no distinction here between posters and oral communications. The Organizers and Editors owe a considerable debt of gratitude to all the contributors who without exception presented the results of their work in a clear and concise manner that did much to reveal the essence of the complex problems central to current thinking on met astasis. Moreover most manuscripts arrived well within the deadline - a circumstance which in our experience is unusual. Of the large audience who attended the Meeting many had come from the far distant corners of the World and to them as well as to the presenters of papers the Organizers wish to express their deep appreciation.
Vitamins and Hormones
First published in 1943, VITAMINS AND HORMONES is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, VITAMINS AND HORMONES continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.*Includes color illustrations*Available on ScienceDirect*Longest running series published by Academic Press *Contributions by leading international authorities
Genes and Genomes
The laws of inheritance were considered quite superficial until 1903, when the chromosome theory of heredity was established by Sutton and Boveri. The discovery of the double helix and the genetic code led to our understanding of gene structure and function. For the past quarter of a century, remarkable progress has been made in the characterization of the human genome in order to search for coherent views of genes. The unit of inheritance termed factor or gene, once upon a time thought to be a trivial an imaginary entity, is now perceived clearly as the precise unit of inheritance that has continually deluged us with amazement by its complex identity and behaviour, sometimes bypassing the u...
The Epigenetic Nature of Early Chordate Development
This volume summarises our present knowledge of inductive interaction during early development of various groups of chordates. Embryonic development is mainly epigenetic, that is, each embryo arises through gradual organisation and emergence of its constituent parts and not by the unfolding of preformed structures. Development as far as the full development of the 'body plan' in the embryo is described. At the beginning of development, there is only very restricted spatial diversity, but as development proceeds the interaction of the different parts leads to ever-increasing spatial complexity of the developing embryo. Interaction starts between the different cell organelles of the oocyte and the, spermatozoon; it continues without interruption between the different parts of the very early embryo and also between the different tissues and organ anlagen of the developing embryo. The new hypothesis as to the nature of the inductive interaction, which is postulated here, is in good agreement with the experimental evidence presented and opens new possibilities for fruitful research into this basic concept of embryonic development.
Handbook of Immunohistochemistry and in situ Hybridization of Human Carcinomas
Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and micr...
Outcome Prediction in Cancer
This book is organized into 4 sections, each looking at the question of outcome prediction in cancer from a different angle. The first section describes the clinical problem and some of the predicaments that clinicians face in dealing with cancer. Amongst issues discussed in this section are the TNM staging, accepted methods for survival analysis and competing risks. The second section describes the biological and genetic markers and the rôle of bioinformatics. Understanding of the genetic and environmental basis of cancers will help in identifying high-risk populations and developing effective prevention and early detection strategies. The third section provides technical details of mathem...
International Review of Cytology
International Review of Cytology
Current Catalog
First multi-year cumulation covers six years: 1965-70.
Advances in Cancer Research
Advances in Cancer Research
