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Recent Advances in Medicine and Health Sciences: Concepts, Researches and Practice
Natural Killer (NK) cells were discovered ca 1975, as the first group of lymphoid cells that were neither T cells nor B cells. Since then, the dissection of the biology of NK cells has been growing exponentially with many seminal discoveries from the identification of MHC class I-specific inhibitory receptors to the discovery of receptor-ligand pairs involved in NK cell activation and to the manipulation of NK cells in cancer. In this research topic, we asked a group of thought leaders in NK cell biology to review recent advances in their origins and biology, and their roles in cancer, infection and inflammation. Together, these 25 articles provide a timely survey of NK cells as critical immunologic components of health and disease. They will hopefully prompt further dialogue and developments in basic and translational immunology.
This book discusses recent research in innate immunity, which has revealed a large number of receptors that sense the presence of microorganisms or cellular damage in tissues. In complex tissues, many of these sensing events occur simultaneously. Thus, the downstream signaling pathways need to be integrated so that an appropriate cellular inflammatory response can be initiated. In addition, the inflammasome defines the molecular and cellular processes of inflammation in response to microbial infection. Previous data suggested that regulation of inflammasomes is mediated by microbes, but inflammasomes also have antimicrobial functions. Increasing evidence in mouse models, together with human ...
Atlas of Pediatric Gastrointestinal Endoscopy focuses on practical diagnostic and therapeutic endoscopy in children. The combining of pediatric endoscopic images with a practical guide to the performance of pediatric gastrointestinal endoscopy makes this volume a unique reference source. The extensive use of black and white line diagrams, color illustrations of endoscopic appearances, and complementary histopathology creates a definitive reference resource for pediatric gastroenterologists and pediatric surgeons. The combined medical and surgical expertise of the authors, garnered from renowned pediatric gastroenterology centers, incorporates both a North American and European perspective. The result is a work that is an integration of clinical gastrointestinal endoscopy with expert pathology. SPECIAL FEATURES * Provides the only reference source of pediatric endoscopic images combined with a practical guide * Includes a thorough selection of endoscopic images, histopathology, and specific radiology images * Features the contributions of leading authors from international pediatric gastroenterology centers