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Magnetic Resonance Imaging of Central Nervous System Diseases
Magnetic resonance imaging (MRI) is a new and still rapidly developing imaging technique which requires a new approach to image interpreta tion. Radiologists are compelled to translate their experience accumulat ed from X-ray techniques into the language of MRI, and likewise stu dents of radiology and interested clinicians need special training in both languages. Out of this necessity emerged the concept of this book as a manual on the application and evaluation of proton MRI for the radiolo gist and as a guide for the referring physician who wants to learn about the diagnostic value of MRI in specific conditions. After a short section on the basic principles of MRI, the contrast mechanisms of present-day imaging techniques, knowledge of which is essential for the analysis of relaxation times, are described in greater de tail. This is followed by a demonstration of functional neuroanatomy us ing three-dimensional view of MR images and a synopsis of frequent neurological symptoms and their topographic correlations, which will fa cilitate examination strategy with respect to both accurate diagnosis and economy.
A Dictionary of German-Jewish Surnames
This dictionary identifies more than 13,000 German-Jewish surnames from the area that was pre-World War I Germany. From Baden-Wuerttemburg in the south to Schleswig-Holstein in the north. From Westfalen in the west to East Prussia in the east. In addition to providing the etymology and variants of each name, it identifies where in the region the name appeared, identifying the town and time period. More than 300 sources were used to compile the book. A chapter provides the Jewish population in many towns in the 19th century.
Kürschners deutscher Gelehrten-Kalender
In der 22. Ausgabe von Kürschners Deutschem Gelehrten-Kalender werden rund 70.000 Wissenschaftlerinnen und Wissenschaftler, die an einer deutschsprachigen wissenschaftlichen Institution tätig sind, vorgestellt. Aufgeführt sind die wichtigsten biographischen Daten, Adressen, Angaben zu Forschungsschwerpunkten und Arbeitsgebieten sowie ausführliche bibliographische Hinweise, u.a. mit einer Auswahl der wichtigsten Veröffentlichungen in Zeitschriften, Sammelwerken und Lexika. Im Anhang finden sich ein Nekrolog, ein Fachgebietsregister, ein Festkalender und schließlich eine Liste aller deutschsprachigen Universitäten und Fachhochschulen. Pluspunkte: Die Einträge werden erstellt auf der Grundlage von Selbstauskünften der eingetragenen Personen und sorgfältiger Recherche. Einzigartige Zusammenstellung und Zuverlässigkeit der Daten, gerade im Vergleich mit dem Internet.
Metallofoldamers
Metallofoldamers are oligomers that fold into three-dimensional structures in a controlled manner upon coordination with metal ions. Molecules in this class have shown an impressive ability to form single-handed helical structures and other three-dimensional architectures. Several metallofoldamers have been applied as sensors due to their selective folding when binding to a specific metal ion, while others show promise for applications as responsive materials on the basis of their ability to fold and unfold upon changes in the oxidation state of the coordinated metal ion, and as novel catalysts. Metallofoldamers: From Helicates to Biomimetic Architectures describes the variety of interactions between oligomers and metal species, with a focus on non-natural synthetic molecules. Topics covered include: the major classes of foldamers and their folding driving force metalloproteins and metalloenzymes helicates: self-assembly, structure and applications abiotic metallo-DNA metallo-PNA and iDNA metallopeptides interactions of biomimetic oligomers with metal ions applications of metallofoldamers
Total Synthesis of (±)-Maoecrystal V
In this thesis, the author describes the total synthesis of natural product Maoecrystal V in detail. In the first part of the thesis, the author introduces the research background and reviews the research progress in total synthesis of Maoecrystal V. In the second part, the author develops a novel and concise approach for the stereo selective construction of the tetracyclic model system of Maoecrystal V. The model system is accomplished in 8 steps with 20% yield. In the third part, the author describes the first successful total synthesis of Maoecrystal V and investigates four strategies for constructing the key tetrahydrofuran oxa-bridge skeleton. The total synthesis starts from a known compound and is accomplished in 17 steps with 1.2% yield. The successful total synthesis of Maoecrystal V will contribute to the development of efficient synthetic strategies for natural products and other compounds with complex structures.
Combinatorial Chemistry
The story of success goes on and on - with a new book on combinatorial chemistry, edited by Gunther Jung! Combinatorial chemistry is a proven time- and resource-saving synthetic method of outstanding importance for industrial processes. Compound libraries help to save time and money, especially in the search for new drugs, and therefore play a pivotal role in solving the problem of the worldwide increasing demand for new and more active drugs. Not only substances, which are of interest for pharmaceutical chemistry, but also materials, catalysts, and biomolecules such as DNA or oligosaccharides are readily available with high structural diversities. The broad scope of combinatorial sciences i...
Foldamers
This truly comprehensive treatise of foldamers, from synthesis to applications in bio-, material-, and nanoscience is at once an introduction to the topic, while providing in-depth accounts on various aspects clearly aimed at the specialist. The book is clearly structured, with the first part concentrating on structure and foldamer design concepts, while the second part covers functional aspects from properties to applications. The international team of expert authors provides overviews of synthetic approaches as well as analytical techniques.
