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Solidarity Between Parents and Their Adult Children in Europe
At present, our knowledge of the current state of solidarity between parents and their adult children in Europe is limited. Insight into contemporary intergenerational solidarity is not only important for the well-being of individuals but is also of great interest to policy makers. Patterns of intergenerational solidarity are not only affected by social policies and services but also reveal a number of important social policy issues and dilemmas. Will encouraging labour force participation among women and older workers mean they have less time to care for their dependents? Should formal care services be further expanded to relieve the burden faced by family members with the risk that they st...
Inflammation and Allergy Drug Design
Our knowledge and understanding of allergic diseases of the respiratory tract has improved to a point where new therapies are being developed for patient benefit. Inflammation and Allergy Drug Design explains the biologic science that underpins the pathophysiology of asthma and related disorders, as well as their mechanisms. This authoritative guide consists of 25 chapters, each detailing the cutting-edge developments in a particular field. It is divided into three parts, covering cytokines, chemokines, grow factors and mediators. This book allows immunologists, allergologists and researchers in the pharmaceutical industry to learn and appreciate the target biology in drug development. It also provides medical and pharmaceutical postgraduate students and clinicians with a basic understanding of allergic diseases in the respiratory tract.
Dendritic Cells
The understanding of the role of dendritic cells (DCs) in immune responses has come a long way since Steinmann and colleagues described these cells in 1972. - tensive research during the intervening period has provided a good understanding of the complexity of the DC system and its pivotal role in immunity. It is also now clearer how different subsets of DCs interact and regulate each other and how DC populations affect the function of other cells of the immune system. The improved understanding of their role in immune response has led to the idea that modulation of DC functions by, for example, pharmacological agents could be used as a pot- tial therapeutic approach in some pathological con...
Games and Learning Alliance
This book constitutes the refereed proceedings of the 4th International Conference on Games and Learning Alliance, GALA 2015, held in Rome, Italy, in December 2015. The 33 revised full papers and 15 short papers presented were carefully reviewed and selected from 102 submissions. The papers presented cover a variety of aspects and knowledge fields. They are grouped around the following topics: games for health, games for mobility, pervasive gaming and urban mobility.
The Inflammasomes
The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease.
Asthma and COPD
The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. * Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management * Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD * Most extensive reference to primary literature on both Asthma and COPD in one source. * Easy-to-read summaries of the latest advances alongside clear illustrations
Warfare and the Age of Printing (4 vols.)
An important part of the Dutch national treasure of early printed books from before 1801 on military and related subjects is kept in military libraries and collections. This catalogue contains 10,000 books in twelve different languages dated 1500–1800 from nine different Defence institutions/collections, representing both Army and Navy. By far the largest collections are the property of the Royal Netherlands Army Museum in Delft and the Royal Netherlands Military Academy in Breda. A great if not substantial part of these books is especially of international significance because of the contents, the intrinsic value or as historical objects. It took eight years to trace and describe these books, all of which have been given extensive analytical bibliographic descriptions. The book includes over 2000 illustrations. The book is a project of the Royal Netherlands Army Museum, Delft
