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Handbook of Experimental Neurology
Basic relevant information on methodologies used in neurological disease models can be extremely hard to find. Originally published in 2006, this important reference work contains 30 chapters from over 60 internationally recognized scientists and covers every major methodology and disease model used in neuroscience research. Divided into two major sections, the first deals with general methodologies in neuroscience research covering topics from animal welfare and ethical issues to surgical procedures, post-operative care and behavioral testing. Section two covers every major disease model including traumatic brain injury, ischemia and stroke, to Parkinson's, motor neurone disease, epilepsy and sleep disorders. Delivering critical methodological information and describing small animal models for almost all major neurological diseases, this book forms an essential reference for anyone working in neuroscience, from beginning students to experienced researchers and medical professionals.
Military Review
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Guild Guitar Book
(Book). Guild guitars have been around since the early 1950s, and by the beginning of the '60s, the company had established a solid reputation for its electric and acoustic archtops, which are still widely regarded today. Despite this enduring popularity, little was known about the history of Guild. The Guild Guitar Book is the result of years of intensive research and countless photo sessions. It includes a thorough history of the company and its guitars, including serial numbers, specifications, original prices, and all the information needed to date Guild guitars. Features hundreds of photos, with a beautiful 40-page color section. Now Back in Print!
Myasthenia Gravis
Autoimmune myasthenia gravis (MG) is a classical autoimmune disease, for which the target antigen, nicotinic acetylcholine receptor, has been cloned, sequenced and biochemically characterized. Antibodies to acetylcholine receptors destroy acetylcholine receptor at the neuromuscular junction, thus leading to defective neuromuscular transmission, muscle fatigue, and weakness. In the last few years, rapid advances have been made in unraveling the cellular and molecular mechanisms involved in the pathogenesis of MG, both in the animal model, experimental autoimmune MG (EAMG), and in human MG. Significant advances are being made in characterizing the cells and molecules involved in the autoimmune...
Chances and Risks in Construction Management and Economics
The book outlines the processes of calculating and critically reviewing construction costs and times for clients and contractors in different project phases. Any project or structural analysis should yield accurate information on times, costs, and prices. The related database is more or less uncertain depending on project complexity and the circumstances of work performance. It is thus recommended to use ranges of key input parameters. This approach consistently considers uncertainties within a holistic project view, thus enhancing the plausibility and validity of specific values. Only the integration of probabilistic methods will allow for calculating and graphically representing the chance...
Collectors’ Knowledge: What Is Kept, What Is Discarded / Aufbewahren oder wegwerfen: wie Sammler entscheiden
Drawing on case studies from the thirteenth to the twentieth centuries, covering Europe and beyond, Collectors’ Knowledge: What is Kept, What is Discarded investigates how knowledge was acquired, organized and sometimes lost. It examines collections of texts and objects—libraries, textbooks, miscellanies, commonplace books, data collections pertaining to historical events, encyclopedias, royal and ducal treasures, curiosity cabinets, galleries and museums—to uncover the processes of accumulation, organization, selection and rejection that have shaped learning. The essays emphasize the complex relationship between the intentions of collectors and the limitations they encountered—issue...
ISTFA 2018: Proceedings from the 44th International Symposium for Testing and Failure Analysis
The International Symposium for Testing and Failure Analysis (ISTFA) 2018 is co-located with the International Test Conference (ITC) 2018, October 28 to November 1, in Phoenix, Arizona, USA at the Phoenix Convention Center. The theme for the November 2018 conference is "Failures Worth Analyzing." While technology advances fast and the market demands the latest and the greatest, successful companies strive to stay competitive and remain profitable.
Myelination and Demyelination
A satellite symposium entitled "Myelination and Demyelination: Recent Chemical Advances" was held in Helsinki from August 29 to 31, 1977, after the Sixth International Meeting of the International Society for Neurochemistry (ISN) in Copenhagen. Myelin is a nervous tissue structure that is most suitable as a subject of biochemical investigation. It is easy to isolate in a highly purified form, is rather stable even after death, and is af fected by a variety of neurological and other diseases. Its lesions are particularly important in the study of multiple sclerosis, a disease which is relatively prevalent in Finland and has therefore been of interest to a great many Finnish scientists. The fi...
