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Antimicrobial Resistance
Development and Implications of Antimicrobial Resistance One of the most ominous trends in the field of antimicrobial chemotherapy over the past decade has been the increasing pace of development of antimicrobial resistance among microbial pathogens. The hypothesis that man can discover a magic bullet to always cure a particular infection has proved false. Physicians are now seeing and treating patients for which there are few therapeutic alternatives, and in some cases, none at all. Until recently there was little concern that physicians might be losing the war in our ability to compete with the evolving resistance patterns of microbial pathogens. Now the general public is very aware of the...
Modeling and Control of Ventilation
The origins of what have come to be known as the "Oxford" Conferences on modelling and the control of breathing can be traced back to a discussion between Dan Cunningham and Richard Hercynski at a conference dinner at the Polish Academy of Sciences in 1971. Each felt that they had benefited from the different perspectives from which the topic of ventilatory control was approached - predominantly physiological in the case of Dr Cunningham and predominantly mathematical in the case of Dr Hercynski. Their judgement at that time was that a conference on the control of breathing which allowed investigators with these different (but related) scientific perspectives to present and discuss their wor...
Oxygen Transport to Tissue XVII
nd The 22 meeting of the International Society on Oxygen Transport to Tissue (LS. O. T. T. ) of which this volume is the scientific proceedings, was held in Istanbul, Turkey on August 22-26, 1994. It was a historical occasion in that it was almost 200 years to the day that one of the founding fathers of oxygen research, Antoine Lavoisier, on May 8, 1794 found his early demise at the hands of the guillotine. This spirit of history set the tone of the conference and in the opening lecture the contribution that this part of the world has given to the understanding of oxygen transport to tissue was highlighted. In particular, the contribution of Galen of Pergamon (129-200) was discussed who for ...
Critical Care Medicine E-Book
Now completely revised to bring you up to date with the latest advances in the field, Critical Care Medicine: Principles of Diagnosis and Management in the Adult, 5th Edition, delivers expert, practical guidance on virtually any clinical scenario you may encounter in the ICU. Designed for intensivists, critical care and pulmonology residents, fellows, practicing physicians, and nurse practitioners, this highly regarded text is clinically focused and easy to reference. Led by Drs. Joseph Parrillo and Phillip Dellinger, the 5th Edition introduces numerous new authors who lend a fresh perspective and contribute their expertise to that of hundreds of top authorities in the field. - Includes new ...
Critical Care Medicine
Take the best possible care of adult critical care patients with Critical Care Medicine: Principles of Diagnosis and Management in the Adult! Editors Dr. Joseph Parrillo and Dr. Phillip Dellinger, two of the most respected names in critical care medicine, combine their extensive knowledge with that of hundreds of top authorities in the field to bring you expert, state-of-the-art answers to any clinical question you may face in the intensive care unit. Offer your adult critical care patients the most effective care with practical, evidence-based guidance from many of the most trusted experts in critical care medicine. Learn from the best ICU specialists worldwide with contributions from an increased number of international authorities. Effectively manage common complications in the ICU with updated coverage of severe sepsis, septic shock, surgical infections, neurogenic and anaphylactic shock, severe heart failure, acute coronary syndromes, and Acute Respiratory Distress Syndrome. Access the complete contents online at Expert Consult, along with an image bank and instructional videos!
Critical Care Medicine
Here’s the most clinically oriented critical care text focusing on the adult patient. In full-color and superbly illustrated with clinical photographs, imaging studies, and management algorithms, and with a broad multidisciplinary focus, this text will help you enhance your skills at any level of training. Stands alone as a clinically oriented comprehensive reference. Completely updated and authorship expanded to reflect the evolution in critical care practice. In color for the first time, with new color schematics and treatment algorithms for greater ease of reference. Utilizes key points lists at the end of chapter, to help you make decisions rapidly and easily. Delivers key references that list other useful resources for information. Includes these seven new chapters to keep you on the cutting edge of your specialty: Assessment of Cardiac Filling and Blood Flow Mechanical Ventilation of Obstructive Airways Disease Mechanical Ventilation of Acute Respiratory Distress Syndrome Severe Sepsis and Multiple Organ Dysfunction Stroke Delirium, Psychosis, Sleep and Depression in the ICU ICU Education
Novel Strategies in the Design and Production of Vaccines
Vaccination is one of the most efficient and cost effective methods of promoting human health and has been in clinical use for at least 200 years. Nevertheless, infectious diseases continue to constitute a constant threat to the well being of humanity. Common pathogens, once believed to be under control, acquire increased virulence and resistance to drugs, while exotic microorganisms emerged from hidden reservoirs to cause yet incurable diseases in humans. These changes, together with epidemic outbreaks related to political and socio-economic instabilities, increase the needs for the development of new, advanced vaccines. In this volume, devoted to the proceedings of the 39th OHOLO Conferenc...
Recent Advances in Cellular and Molecular Aspects of Angiotensin Receptors
Scientific advances over the past two decades have afforded unprecedented oppor tunities to understand the structure and function of receptors, receptor-ligand interactions, and receptor signaling. The extent ofprogress in this area is underscored by the recent Nobel Prize for Medicine and Physiology to Alfred Gilman and Martin Rodbell, both of whose work in understanding receptorlG-protein interactions has redefined the way in which we think of how hormones and neurochemicals exert their activity on cellular function. This book is replete with examples of current research approaches to help us better understand the cellular roles in which the renin-angiotensin system and the angiotensin rec...
Antiviral Chemotherapy 4
The three years since our last conference in San Francisco have again seen a dramatic expansion of the number of antivirals either licensed or in the late stages of clinical trials. d4T is now licensed for HIV infection, famciclovir and the oral pro-drug of acyclovir, valacyclovir, are now licensed for VZV infections in some countries. Moreover. oral ganciclovir, cidofovir, and sorivudine are not far behind. Clinical trials with the second-site reverse transcriptase inhibitors and the protease inhibitors for HlV infection are proceeding rapidly and on a broad scale, and the preliminary results would suggest that several of these classes of drugs will be licensed as well. Despite this optimis...
Gastrointestinal Emergencies
Discusses the epidemiology, pathophysiology, clinical presentation, differential diagnosis, and treatment of gastrointestinal emergencies. Some of the topics covered--such as typhlitis, the acute abdomen in pregnancy, graft versus host disease, phlegmonous gastritis, and chemical and drug-induced colitis--are not found in most gastrointestinal textbooks. Other topics discussed include pediatric emergencies, infections of the esophagus in the immunocompromised host, intestinal and hepatic complications of bone marrow and stem cell transplantation, gastrointestinal complications of AIDS, foreign bodies in the gastrointestinal tract, caustic ingestions, and alcoholic hepatitis. Annotation copyright by Book News, Inc., Portland, OR
