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Excitatory Amino Acid Receptors
Designed to reflect the growing awareness of the chemical aspects of excitatory amino acids, this text uses computer-based methods and X-ray techniques to depict and analyze molecules and structure-activity relationships. The book incorporates stereochemical principles into all analyses.
Mechanosensitive Ion Channels, Part B
Current Topics in Membranes provides a systematic, comprehensive, and rigorous approach to specific topics relevant to the study of cellular membranes. Each volume is a guest edited compendium of membrane biology. This series has been a mainstay for practicing scientists and students interested in this critical field of biology. Articles covered in the volume include ENaC Proteins in Vascular Smooth Muscle Mechanotransduction; Regulation of the Mechano-Gated K2P Channel TREK-1 by Membrane Phospholipids; MechanoTRPs and TRPA1; TRPC; The Cytoskeletal Connection to Ion Channels as a Potential Mechanosensory Mechanism. Lessons From Polycystin-2 (TRPP2); Lipid Stress at Play: Mechanosensitivity o...
Honoré Fabri and the Concept of Impetus: A Bridge between Conceptual Frameworks
This book discusses the impetus-based physics of the Jesuit natural philosopher and mathematician Honoré Fabri (1608-1688), a senior representative of Jesuit scientists during the period between Galileo's death (1642) and Newton's Principia (1687). It shows how Fabri, while remaining loyal to a general Aristotelian outlook, managed to reinterpret the old concept of “impetus” in such a way as to assimilate into his physics building blocks of modern science, like Galileo’s law of fall and Descartes’ principle of inertia. This account of Fabri’s theory is a novel one, since his physics is commonly considered as a dogmatic rejection of the New Science, not essentially different from the medieval impetus theory. This book shows how New Science principles were taught in Jesuit Colleges in the 1640s, thus depicting the sophisticated manner in which new ideas were settling within the lion’s den of Catholic education.
Ion Channel Drug Discovery
A rapidly growing field, this book covers the recent advances in screening technology, ion channel structure and modelling, with up-to-date case histories.
Excitatory Amino Acids and Synaptic Transmission
Excitatory amino acids (EAAs) as neurotransmitters are the subject of vast and rapidly expanding interest. The First Edition of Excitatory Amino Acids and Synaptic Transmission was the first text to provide anoverview of the function of EAAs in transmission at the synapses and in the organization of the nervous system. The First Edition is a well-respected reference text for neuroscience researchers; it provides a comprehensive account of the physiological, pharmacological, chemical, molecular, biological, and neural networking aspects of the EAAs. The Second Edition has been revised so that its text is even more user-friendly; plus its coverage has been expanded to include the up-to-date approaches of molecular biology and biophysics. The well-praised explanatory glossary has also been improved.
Sensing with Ion Channels
This is the first book that is not exclusively focused on ion channels functioning in sensory mechanisms that are characteristic of animals and humans, but also describes the role of ion channels in signal transduction mechanisms found in microbial cells and plants. It summarizes comprehensively the progress that has been made in studies of ion channels and their role in sensory physiology.
Introduction to Pharmaceutical Chemical Analysis
This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in “analytical chemistry” for the 5 years pharmacy curriculum, but the textbook is also intended for analytical chemists moving into the field of pha...
Mechanosensitive Ion Channels
This book explores the latest data dealing with mechanosensitive channels research results. It was compiled by a group of internationally recognized scientists leading in the field of mechanosensitive ion channels or mechanically gated channels and signaling cascades research. Key problems of cell mechanobiology are also discussed. As a whole, the volume dwells on the major issues of mechanical stress influencing the ion channels and intracellular signaling pathways.
