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The Technologist
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Submitted Papers
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Paediatric Formulation
The development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the need for dose flexibility; route of administration; patient compliance; excipient tolerability. For example, the toxicity of excipients may differ in children compared to adults and children have different taste preferences. Globally, about 75% of drugs do not carry regulatory approval for use in children; worldwide, many medications prescribed for the treatment of paediatric diseases are used off-label, and less than 20% of package inserts have sufficient information for treating children. This book provides an update on both state-of-the-art methodology and operational challenges in paediatric formulation design and development. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients.
Applied Agrometeorology
Farmers Agricultural policymakers Environmentalists
Phytoremediation
This text details the plant-assisted remediation method, “phytoremediation," which involves the interaction of plant roots and associated rhizospheric microorganisms for the remediation of soil contaminated with high levels of metals, pesticides, solvents, radionuclides, explosives, crude oil, organic compounds and various other contaminants. Each chapter highlights and compares the beneficial and economical alternatives of phytoremediation to currently practiced soil removal and burial practices.
Agatha Christie’s The Mysterious Affair at Styles in German and Dutch Translation
Agatha Christie is one of the most popular and most translated authors of all time. Yet there is little academic work on her writing. This book sets out to rectify this. No matter where in the world you are, Hercule Poirot is a name that conjures up certain associations. The detailed analysis of the original text, three German and two Dutch translations of The Mysterious Affair at Styles however shows that his depiction differs immensely between the individual texts. In the course of this book, reasons for these differences are found via the analysis of the shifts of status of Agatha Christie as an author of detective fiction and of translations from English in Germany and the Netherlands. During this exploration the discovery will be made that, when translated, escapist literature such as Christie’s detective fiction actually becomes a highly political affair.
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Chemistry of Carbon Nanostructures
Chemistry of Carbon Nanostructures aims to present the current state-of-the-art synthesis and application of carbon materials like nano diamonds, ribbons and graphene-like structures in science and engineering. Edited by Professor Klaus Müllen, who received the Adolf von Bayer Medal for his contribution to Carbon Chemistry, and Xinliang Feng, this book combines outstanding contributions by a renowned international team of experts. The authors discuss chemical aspects of carbon nanostructures, their synthesis, functionalization and design strategies for defi ned applications. Recent advances in carbon nanomembranes, molecule-assisted ultrasound-induced liquid-phase exfoliation of graphene, and solution synthesis of graphene nanoribbons and biological application of nanodiamonds are highlighted topics. This book provides an excellent reference on the chemistry of carbon nanostructures for Chemists, Materials Scientists, Condensed-matter Physicists, Surface Scientists, and Engineers.
